Articles

The effect of hemorrhagic shock and intraosseous adrenaline injection on the delivery of a subsequently administered drug - an experimental study

Intraosseous (IO) access is a recommended method when venous access cannot be rapidly established in an emergency. Experimental data suggest that major hemorrhage and catecholamine administration both reduce b...

Authors: Mats Eriksson, Anders Larsson, Miklós Lipcsey and Gunnar Strandberg

Treatment delay in status epilepticus – more effective prehospital symptom recognition warranted

The outcome of status epilepticus (SE) can be improved by facilitating early recognition and treatment with antiepileptic drugs. The purpose of this study was to analyze the treatment delay of SE in a prospect...

Authors: Joni J. Sairanen, Anne-Mari Kantanen, Harri T. Hyppölä and Reetta K. Kälviäinen

Interhospital transport of critically ill patients: experiences and challenges, a qualitative study

No consensus based national standard for interhospital transports of critically ill patients exists in Norway. The local hospitals are responsible for funding, organizing and performing these transports, resul...

Authors: Helge Eiding, Ulf E. Kongsgaard and Anne-Cathrine Braarud

Unplanned out-of-hospital birth and risk factors of adverse perinatal outcome: findings from a prospective cohort

In France, while most babies are delivered at hospital, emergency medical services (EMS) weekly manage calls for unplanned out-of-hospital births. The objective of our study was to describe neonatal morbidity ...

Authors: François Javaudin, Valérie Hamel, Arnaud Legrand, Sybille Goddet, François Templier, Christine Potiron, Philippe Pes, Gilles Bagou and Emmanuel Montassier

Impact of initial coagulation and fibrinolytic markers on mortality in patients with severe blunt trauma: a multicentre retrospective observational study

Acute coagulopathy is a well-known predictor of poor outcomes in patients with severe trauma. However, using coagulation and fibrinolytic markers, how one can best predict mortality to find out potential candi...

Authors: Kenta Ishii, Takahiro Kinoshita, Kazutaka Kiridume, Atsushi Watanabe, Kazuma Yamakawa, Shota Nakao, Satoshi Fujimi and Tetsuya Matsuoka

Changes in anaesthetic use for trauma patients in German HEMS – a retrospective study over a ten-year period

Airway management and use of intravenous anaesthetics to facilitate tracheal intubation after major trauma remains controversial. Numerous agents are available and used for pre-hospital rapid-sequence inductio...

Authors: Arasch Wafaisade, Michael Caspers, Bertil Bouillon, Matthias Helm, Matthias Ruppert and Michael Gäßler

Inhaled nitric oxide might be a contributing tool for successful resuscitation of cardiac arrest related to pulmonary hypertension

We describe a case where inhaled nitric oxide (iNO) was successfully initiated during cardiopulmonary resuscitation (CPR) in a younger patient with cardiac arrest related to pulmonary hypertension after dissem...

Authors: Per P. Bredmose, Christian Buskop and Anne Birthe Lømo

Connect dispatch centers for call handling improves performance

The aim of this Letter to the Editor was to report a strategy to reduce time waiting for emergency calls in a dispatch center, in line with a recently published article that reviewed evidence for medical dispa...

Authors: Yann Penverne, Michel Terré, François Javaudin, Joël Jenvrin, Frédéric Berthier, Julien Labady, Brice Leclere and Emmanuel Montassier

Airway Management in the Emergency Department (The OcEAN-Study) - a prospective single centre observational cohort study

Emergency airway management (AM) is a major key for successful resuscitation of critically ill non-traumatic (CINT) patients. Details of the AM of these patients in German emergency departments (ED) are unknow...

Authors: Michael Bernhard, Sönke Nils Bax, Thomas Hartwig, Maryam Yahiaoui-Doktor, Sirak Petros, Sven Bercker, Alexandra Ramshorn-Zimmer and André Gries

Sepsis: mechanisms of bacterial injury to the patient

In bacteremia the majority of bacterial species are killed by oxidation on the surface of erythrocytes and digested by local phagocytes in the liver and the spleen. Sepsis-causing bacteria overcome this mechan...

Authors: Hayk Minasyan

Does injury pattern among major road trauma patients influence prehospital transport decisions regardless of the distance to the nearest trauma centre? – a retrospective study

Prehospital undertriage occurs when the required level of care for a major trauma patient is underestimated and the patient is transported to a lower-level emergency care facility. One possible reason is that ...

Authors: Helen Fagerlind, Lara Harvey, Stefan Candefjord, Johan Davidsson and Julie Brown

Challenges of helicopter mountain rescue missions by human external cargo: need for physicians onsite and comprehensive training

Human external cargo (HEC) extrication during helicopter rescue missions is commonly used in mountain emergency medical services. Furthermore, longline or winch operations offer the opportunity to deliver prof...

Authors: Urs Pietsch, Giacomo Strapazzon, Dimitri Ambühl, Volker Lischke, Simon Rauch and Jürgen Knapp

Is there an association between female gender and outcome in severe trauma? A multi-center analysis in the Netherlands

Little evidence suggest that female gender is associated with a lower risk of mortality in severely injured patients, especially in premenopausal women. Previous clinical studies have shown contradictory resul...

Authors: M. Pape, G. F. Giannakópoulos, W. P. Zuidema, E. S. M. de Lange-Klerk, E. J. Toor, M. J. R. Edwards, M. H. J. Verhofstad, T. N. Tromp, E. M. M. van Lieshout, F. W. Bloemers and L. M. G. Geeraedts

Comparison of two different intraosseous access methods in a physician-staffed helicopter emergency medical service – a quality assurance study

Intravenous access in critically ill and injured patients can be difficult or impossible in the field. Intraosseous access is a well-established alternative to achieve access to a noncollapsible vascular netwo...

Authors: Renate Sørgjerd, Geir Arne Sunde and Jon-Kenneth Heltne

Permissive hypotensive resuscitation in patients with traumatic hemorrhagic shock

We read the article “Risks and benefits of hypotensive resuscitation in patients with traumatic hemorrhagic shock: a meta-analysis” by Natthida Owattanapanich et al. with great interest and found it to be insi...

Authors: Kai-Hung Ho, Yih-Wen Tarng, Yi-Pin Chou and Hsing-Lin Lin

Impact of icing weather conditions on the patients in helicopter emergency medical service: a prospective study from Northern Finland

A high number of denied or cancelled HEMS missions are caused by poor weather conditions especially during winter season. Furthermore, many helicopter manufacturers have denied their helicopters to be operated...

Authors: Ilkka Pulkkinen, Jari Pirnes, Ari Rissanen and Päivi Laukkanen-Nevala

Rating the quality of teamwork—a comparison of novice and expert ratings using the Team Emergency Assessment Measure (TEAM) in simulated emergencies

Training in teamwork behaviour improves technical resuscitation performance. However, its effect on patient outcome is less clear, partly because teamwork behaviour is difficult to measure. Furthermore, it is ...

Authors: Julia Freytag, Fabian Stroben, Wolf E. Hautz, Stefan K. Schauber and Juliane E. Kämmer

Prehospital intravenous fentanyl administered by ambulance personnel: a cluster-randomised comparison of two treatment protocols

Prehospital acute pain is a frequent symptom that is often inadequately managed. The concerns of opioid induced side effects are well-founded. To ensure patient safety, ambulance personnel are therefore provid...

Authors: Kristian D. Friesgaard, Hans Kirkegaard, Claus-Henrik Rasmussen, Matthias Giebner, Erika F. Christensen and Lone Nikolajsen

“Hand hygiene perception and self-reported hand hygiene compliance among emergency medical service providers: a Danish survey”

Hand hygiene (HH), a cornerstone in infection prevention and control, lacks quality in emergency medical services (EMS). HH improvement includes both individual and institutional aspects, but little is known a...

Authors: Heidi Storm Vikke, Svend Vittinghus, Martin Betzer, Matthias Giebner, Hans Jørn Kolmos, Karen Smith, Maaret Castrén, Veronica Lindström, Marja Mäkinen, Heini Harve and Christian Backer Mogensen

Prehospital on-scene anaesthetist treating severe traumatic brain injury patients is associated with lower mortality and better neurological outcome

Patients with isolated traumatic brain injury (TBI) are likely to benefit from effective prehospital care to prevent secondary brain injury. Only a few studies have focused on the impact of advanced interventi...

Authors: Toni Pakkanen, Jouni Nurmi, Heini Huhtala and Tom Silfvast

Medical dispatchers’ perception of visual information in real out-of-hospital cardiac arrest: a qualitative interview study

Authors: Gitte Linderoth, Thea Palsgaard Møller, Fredrik Folke, Freddy K. Lippert and Doris Østergaard

Penetrating stab injuries in Iceland: a whole-nation study on incidence and outcome in patients hospitalized for penetrating stab injuries

Studies on penetrating injuries in Europe are scarce and often represent data from single institutions. The aim of this study was to describe the incidence and demographic features of patients hospitalized for...

Authors: Una Johannesdottir, Gudrun Maria Jonsdottir, Bergros K. Johannesdottir, Alexandra Aldis Heimisdottir, Elias Eythorsson, Tomas Gudbjartsson and Brynjolfur Mogensen

Best practice advice on pre-hospital emergency anaesthesia & advanced airway management

Effective and timely airway management is a priority for sick and injured patients. The benefit and conduct of pre-hospital emergency anaesthesia (PHEA) and advanced airway management remains controversial but...

Authors: Kate Crewdson, David Lockey, Wolfgang Voelckel, Peter Temesvari and Hans Morten Lossius

Patient and rescuer safety: recommendations for dispatch and prioritization of rescue resources based on a retrospective study of Norwegian avalanche incidents 1996–2017

Avalanche emergency response should address current accident scenarios to optimize survival chances of victims and to keep rescuers safe. The purpose of this article is to present a basis for evaluation and ne...

Authors: Albert Lunde and Christen Tellefsen

Hospital level variations in the trends and outcomes of the nonoperative management of splenic injuries – a nationwide cohort study

The long-term treatment trends of splenic injuries can provide guidance when treating trauma patients. The nonoperative management (NOM) of splenic injuries was introduced in early 1989. After decades of devel...

Authors: Chien-An Liao, Yu-Tung Wu, Chien-Hung Liao, Shang-Yu Wang, Chih-Yuan Fu, Chi-Hsun Hsieh, Shao-Wei Chen, Ching-Chang Chen, An-Hsun Chou and Chi-Tung Cheng

Pre-hospital management of acute stroke patients eligible for thrombolysis – an evaluation of ambulance on-scene time

Stroke is a leading cause of death and disability with effective treatment, including thrombolysis or thrombectomy, being time-critical for favourable outcomes. While door-to-needle time in hospital has been o...

Authors: Nicolas Drenck, Søren Viereck, Josefine Stokholm Bækgaard, Karl Bang Christensen, Freddy Lippert and Fredrik Folke

Actual clinical leadership: a shadowing study of charge nurses and doctors on-call in the emergency department

The provision of safe, high quality healthcare in the Emergency Department (ED) requires frontline healthcare personnel with sufficient competence in clinical leadership. However, healthcare education curricul...

Authors: Sissel Eikeland Husebø and Øystein Evjen Olsen

Training and assessment of non-technical skills in Norwegian helicopter emergency services: a cross-sectional and longitudinal study

Deficient non-technical skills (NTS) among providers of critical care in helicopter emergency medical services (HEMS) is a threat to patient and operational safety. Skills can be improved through simulation-ba...

Authors: Kristen Rasmussen, Henrik Langdalen, Stephen J. M. Sollid, Eirik Bjorheim Abrahamsen, Leif Inge K. Sørskår, Gunnar Tschudi Bondevik and Håkon B. Abrahamsen

The final assessment and its association with field assessment in patients who were transported by the emergency medical service

In patients who call for the emergency medical service (EMS), there is a knowledge gap with regard to the final assessment after arriving at hospital and its association with field assessment.

Authors: Carl Magnusson, Christer Axelsson, Lena Nilsson, Anneli Strömsöe, Monica Munters, Johan Herlitz and Magnus Andersson Hagiwara

Comparison of a novel, endoscopic chest tube insertion technique versus the standard, open technique performed by novice users in a human cadaver model: a randomized, crossover, assessor-blinded study

The technique of tube thoracostomy has been standardized for years without significant updates. Alternative procedural methods may be beneficial in certain prehospital and inpatient environments with limited r...

Authors: Byron C. Drumheller, Anthony Basel, Sakib Adnan, Joseph Rabin, Jason D. Pasley, Jason Brocker and Samuel M. Galvagno Jr

Effects of NaHS and hydroxylamine on the expressions of brain-derived neurotrophic factor and its receptors in rats after cardiac arrest and cardiopulmonary resuscitation

H₂S can also protect nerve cells. The objective of the study is to investigate the effects of hydrogen sulfide (H₂S) on the expressions of brain-derived neurotrophic factor (BDNF) and its receptors, tyrosine prot...

Authors: Jiyan Lin, Weicheng Wu, Zhihong Xu, Siyao Liu, Wang Lu and Mandong Pan

Survival of in-hospital cardiac arrest in men and women in a large Swedish cohort

Cardiac arrest is more common in men than women and a few studies have shown inferior 30-day survival for men than for women. The difference might relate to patient characteristics, intra arrest factors or pos...

Authors: Angelika Qvick, Manar Radif, Caroline Brever, Jenny Olsson Myrvik, Karin Schenk Gustafsson and Therese Djärv

Risks and benefits of hypotensive resuscitation in patients with traumatic hemorrhagic shock: a meta-analysis

Damage control strategies play an important role in trauma patient management. One such strategy, hypotensive resuscitation, is being increasingly employed. Although several randomized controlled trials have r...

Authors: Natthida Owattanapanich, Kaweesak Chittawatanarat, Thoetphum Benyakorn and Jatuporn Sirikun

Prognostic value of gasping for short and long outcomes during out-of-hospital cardiac arrest: an updated systematic review and meta-analysis

We systematically reviewed the literature to investigate whether gasping could predict short and long outcomes in patients with out of hospital cardiac arrest (OHCA).

Authors: Qiang Zhang, Bo Liu, Zhijiang Qi and Chunsheng Li

Factors associated with acute kidney injury in the Helsinki Burn Centre in 2006–2015

Acute kidney injury (AKI) is a common complication in severe burns and can lead to significantly poorer outcomes. Although the prognosis has improved in recent decades, the mortality of AKI remains considerabl...

Authors: I. Rakkolainen, J. V. Lindbohm and J. Vuola

Investigating the ability of non-invasive measures of cardiac output to detect a reduction in blood volume resulting from venesection in spontaneously breathing subjects

Monitoring cardiac output (CO) in shocked patients provides key etiological information and can be used to guide fluid resuscitation to improve patient outcomes. Previously this relied on invasive monitoring, ...

Authors: Benjamin Mothibe Bussmann, William Hulme, Andrew Tang and Tim Harris

ECMO improves survival following cardiogenic shock due to carbon monoxide poisoning - an experimental porcine model

Severe intoxication with carbon monoxide (CO) is extremely lethal and causes numerous deaths due to cardiac or respiratory failure. Conventional intensive treatment may not be sufficient. The aim of this study...

Authors: Carsten Simonsen, Sigridur O. Magnusdottir, Jan J. Andreasen, Marianne Cathrine Rohde and Benedict Kjærgaard

Traumatic brain injury is associated with increased syndecan-1 shedding in severely injured patients

Head injury and exsanguination are the leading causes of death in trauma patients. Hemorrhagic shock triggers systemic endothelial glycocalyx breakdown, potentially leading to traumatic endotheliopathy (EoT). ...

Authors: Erika Gonzalez Rodriguez, Jessica C. Cardenas, Charles S. Cox, Ryan S. Kitagawa, Jakob Stensballe, John B. Holcomb, Pär I. Johansson and Charles E. Wade

Seven years since defining the top five research priorities in physician-provided pre-hospital critical care – what did it lead to and where are we now?

Authors: Kristi G. Bache, Marius Rehn and Julian Thompson

Mortality of civilian patients with suspected traumatic haemorrhage receiving pre-hospital transfusion of packed red blood cells compared to pre-hospital crystalloid

Major haemorrhage is a leading cause of mortality following major trauma. Increasingly, Helicopter Emergency Medical Services (HEMS) in the United Kingdom provide pre-hospital transfusion with blood products, ...

Authors: J. E. Griggs, J. Jeyanathan, M. Joy, M. Q. Russell, N. Durge, D. Bootland, S. Dunn, E. D. Sausmarez, G. Wareham, A. Weaver and R. M. Lyon

Comment to: non-specific complaints at emergency department presentation result in unclear diagnoses and lengthened hospitalization: a prospective observational study

Authors: Roland Bingisser and Christian H Nickel

Factors determining level of hospital care and its association with outcome after resuscitation from pre-hospital pulseless electrical activity

Patients resuscitated from out-of-hospital cardiac arrest (OHCA) with pulseless electrical activity (PEA) as initial cardiac rhythm are not always treated in intensive care units (ICUs): some are admitted to h...

Authors: Sini SAARINEN, Ari SALO, James BOYD, Päivi LAUKKANEN-NEVALA, Catharina SILFVAST, Ilkka VIRKKUNEN and Tom SILFVAST

Bone marrow-derived mononuclear cell therapy can attenuate systemic inflammation in rat heatstroke

This study was performed to gain insights into novel therapeutic approaches for acute systemic inflammation in heatstroke. Bone marrow-derived mononuclear cells (BMMNCs) secrete anti-inflammatory proteins and ...

Authors: Yutaka Umemura, Hiroshi Ogura, Hiroshi Matsuura, Takeshi Ebihara, Kentaro Shimizu and Takeshi Shimazu

The role of a checklist for assessing the quality of basic life support performance: an observational cohort study

Training lay rescuers in Basic Life Support (BLS) is essential to improve bystander cardiopulmonary resuscitation (CPR) rates; in addition, simple methods are needed to provide feedback on CPR performance. Thi...

Authors: Johanna van Dawen, Lina Vogt, Hanna Schröder, Rolf Rossaint, Lina Henze, Stefan K. Beckers and Saša Sopka

Identification and internal validation of models for predicting survival and ICU admission following a traumatic injury

Measures to improve the accuracy of determining survival and intensive care unit (ICU) admission using the International Classification of Injury Severity Score (ICISS) are not often conducted on a population-...

Authors: Rebecca J. Mitchell, Hsuen P. Ting, Tim Driscoll and Jeffrey Braithwaite

The accuracy of medical dispatch - a systematic review

It is a challenge to dispatch Emergency medical Services (EMS) appropriately with limited resources and maintaining patient safety; this requires accurate dispatching systems. The objective of the current syst...

Authors: K. Bohm and L. Kurland

A prediction model for good neurological outcome in successfully resuscitated out-of-hospital cardiac arrest patients

In the initial hours after out-of-hospital cardiac arrest (OHCA), it remains difficult to estimate whether the degree of post-ischemic brain damage will be compatible with long-term good neurological outcome. ...

Authors: Ward Eertmans, Thao Mai Phuong Tran, Cornelia Genbrugge, Laurens Peene, Dieter Mesotten, Jo Dens, Frank Jans and Cathy De Deyne

Treat me nice! –a cross-sectional study examining support during the first year in the emergency medical services

Working in the emergency medical service (EMS) can be extremely varying and sometimes physically and psychologically demanding. Being new in this context can be a great challenge. This study aim to describe wh...

Authors: Anna Hörberg, Susanne Kalén, Maria Jirwe, Max Scheja and Veronica Lindström

A retrospective comparison between non-conveyed and conveyed patients in ambulance care

Not all patients where an ambulance is dispatched are conveyed to an emergency department. Although non-conveyance is a substantial part of ambulance care, there is limited insight in the non-conveyance patien...

Authors: Lilian C. M. Vloet, Arjan de Kreek, Emmelieke M. C. van der Linden, Jori J. A. van Spijk, Vince A. H. Theunissen, Maud van Wanrooij, Pierre M. van Grunsven and Remco H. A. Ebben

Best practice guidelines for blunt cerebrovascular injury (BCVI)

Blunt cerebrovascular injury (BCVI) is a non-penetrating injury to the carotid and/or vertebral artery that may cause stroke in trauma patients. Historically BCVI has been considered rare but more recent publi...

Authors: Tor Brommeland, Eirik Helseth, Mads Aarhus, Kent Gøran Moen, Stig Dyrskog, Bo Bergholt, Zandra Olivecrona and Elisabeth Jeppesen