Articles

Pre-hospital extra-corporeal cardiopulmonary resuscitation

Survival from out-of-hospital cardiac arrest (OHCA) has remained low despite advances in resuscitation science. Hospital-based extra-corporeal cardiopulmonary resuscitation (ECPR) is a novel use of an establis...

Authors: Ben Singer, Joshua C. Reynolds, David J. Lockey and Ben O’Brien

Review of 14 drowning publications based on the Utstein style for drowning

The Utstein style for drowning (USFD) was published in 2003 with the aim of improving drowning research. To support a revision of the USFD, the current study aimed to generate an inventory of the use of the US...

Authors: Allart M. Venema, Anthony R. Absalom, Ahamed H. Idris and Joost J. L. M. Bierens

Response to: pre-hospital advanced airway management in children: a challenge that training can handle

Authors: Mona Tarpgaard

First installation of a dual-room IVR-CT system in the emergency room

Computed tomography (CT) embedded in the emergency room has gained importance in the early diagnostic phase of trauma care. In 2011, we implemented a new trauma workflow concept with a sliding CT scanner syste...

Authors: Daiki Wada, Yasushi Nakamori, Shuji Kanayama, Shuhei Maruyama, Masahiro Kawada, Hiromu Iwamura, Koichi Hayakawa, Fukuki Saito and Yasuyuki Kuwagata

Bedside analysis of the sublingual microvascular glycocalyx in the emergency room and intensive care unit – the GlycoNurse study

Deterioration of the endothelial glycocalyx (eGC), a protective carbohydrate-rich layer lining the luminal surface of the endothelium, plays a key role in vascular barrier dysfunction and eventually organ-fail...

Authors: Alexandros Rovas, Alexander-Henrik Lukasz, Hans Vink, Marc Urban, Jan Sackarnd, Hermann Pavenstädt and Philipp Kümpers

Effect of gelatin-polysuccinat on cerebral oxygenation and microcirculation in a porcine haemorrhagic shock model

During early treatment of haemorrhagic shock maintenance of cerebral and end-organ oxygen supply by fluid resuscitation is mandatory. Gelatin-polysuccinat (GP) recently regained attention despite a still uncle...

Authors: Alexander Ziebart, Christian Möllmann, Andreas Garcia-Bardon, Jens Kamuf, Moritz Schäfer, Rainer Thomas and Erik K. Hartmann

Predictors of hospital mortality in adult trauma patients receiving extracorporeal membrane oxygenation for advanced life support: a retrospective cohort study

Using extracorporeal membrane oxygenation (ECMO) to provide advanced life support in adult trauma patients remains a controversial issue now. The study was aimed at identifying the independent predictors of ho...

Authors: Meng-Yu Wu, Pin-Li Chou, Tzu-I Wu and Pyng-Jing Lin

Perceptions and experiences of community first responders on their role and relationships: qualitative interview study

Community First Responders (CFRs) are lay volunteers who respond to medical emergencies. We aimed to explore perceptions and experiences of CFRs in one scheme about their role.

Authors: Viet-Hai Phung, Ian Trueman, Fiona Togher, Roderick Ørner and Aloysius Niroshan Siriwardena

Hypoglycaemia without diabetes encountered by emergency medical services: a retrospective cohort study

The current study investigates the incidence, aetiology, and outcome of hypoglycaemia of patients without diabetes in the EMS.

Authors: Hanna Vihonen, Markku Kuisma and Jouni Nurmi

suPAR is associated with risk of future acute surgery and post-operative mortality in acutely admitted medical patients

Acutely admitted medical patients are often fragile and in risk of future surgery. The biomarker soluble urokinase plasminogen activator receptor (suPAR) is a predictor of readmission and mortality in the acut...

Authors: Jeppe Meyer, Morten Alstrup, Line J. H. Rasmussen, Martin Schultz, Steen Ladelund, Thomas H. Haupt, Jens Tingleff, Kasper Iversen and Jesper Eugen-Olsen

Sensemaking in the formation of basic life support teams - a proof-of-concept, qualitative study of simulated in-hospital cardiac arrests

The formation of critical care teams is a complex process where team members need to get a shared understanding of a serious situation. No previous studies have focused on how this shared understanding is achi...

Authors: Peter Hallas, Johnny Lauridsen and Mikkel Brabrand

What should be included in the assessment of laypersons’ paediatric basic life support skills? Results from a Delphi consensus study

Assessment of laypersons’ Paediatric Basic Life Support (PBLS) skills is important to ensure acquisition of effective PBLS competencies. However limited evidence exists on which PBLS skills are essential for l...

Authors: Asbjørn Børch Hasselager, Torsten Lauritsen, Tim Kristensen, Cathrine Bohnstedt, Claus Sønderskov, Doris Østergaard and Martin Grønnebæk Tolsgaard

Patient and case characteristics associated with ‘no paramedic treatment’ for low-acuity cases referred for emergency ambulance dispatch following a secondary telephone triage: a retrospective cohort study

Predicting case types that are unlikely to be treated by paramedics can aid in managing demand for emergency ambulances by identifying cases suitable for alternative management pathways. The aim of this study ...

Authors: Kathryn Eastwood, Amee Morgans, Johannes Stoelwinder and Karen Smith

Danish first aid books compliance with the new evidence-based non-resuscitative first aid guidelines

The European Resuscitation Council (ERC) released new guidelines on resuscitation in 2015. For the first time, the guidelines included a separate chapter on first aid for laypersons. We analysed the current ma...

Authors: Theo Walther Jensen, Thea Palsgaard Møller, Søren Viereck, Jens Roland, Thomas Egesborg Pedersen and Freddy K. Lippert

Severe thoracic trauma – still an independent predictor for death in multiple injured patients?

Over the past, the severe thoracic trauma has had decisive influence on the outcome of multiple injured patients. Today, new therapies (e.g. extracorporeal membrane oxygenation (ECMO), protective ventilation m...

Authors: Michael Grubmüller, Maximilian Kerschbaum, Eva Diepold, Katharina Angerpointner, Michael Nerlich and Antonio Ernstberger

Long-term mortality of acetaminophen poisoning: a nationwide population-based cohort study with 10-year follow-up in Taiwan

The long-term mortality of acetaminophen (APAP) poisoning has not yet been well studied; hence, we conducted this study to gain understanding of this issue.

Authors: Hung-Sheng Huang, Chung-Han Ho, Shih-Feng Weng, Chien-Chin Hsu, Jhi-Joung Wang, Shih-Bin Su, Hung-Jung Lin and Chien-Cheng Huang

Comparison of two different coagulation algorithms on the use of allogenic blood products and coagulation factors in severely injured trauma patients: a retrospective, multicentre, observational study

At the University Hospital Zurich (USZ) and the Cantonal Hospital of Lucerne (LUKS) an individualized goal-directed coagulation and transfusion algorithm was introduced and implemented before 2012 (Coagulation...

Authors: Alexander Kaserer, Mattias Casutt, Kai Sprengel, Burkhardt Seifert, Donat R. Spahn and Philipp Stein

Prognostic value of coagulation tests for in-hospital mortality in patients with traumatic brain injury

Coagulopathy is commonly observed after traumatic brain injury (TBI). However, it is not known whether using the standard independent predictors in conjunction with coagulation tests would improve their progno...

Authors: Qiang Yuan, Jian Yu, Xing Wu, Yi-rui Sun, Zhi-qi Li, Zhuo-ying Du, Xue-hai Wu and Jin Hu

Paediatric medical emergency calls to a Danish Emergency Medical Dispatch Centre: a retrospective, observational study

Little is known regarding paediatric medical emergency calls to Danish Emergency Medical Dispatch Centres (EMDC). This study aimed to investigate these calls, specifically the medical issues leading to them an...

Authors: Kasper Andersen, Søren Mikkelsen, Gitte Jørgensen and Stine Thorhauge Zwisler

Emergency medicine for 25 Years in Iceland – history of the specialty in a nutshell

After the early implementation of Emergency Medicine (EM) 25 years ago, Iceland became the first Nordic country to nationally realize the benefits of this specialty. However, the road has been rocky as in many...

Authors: Jón Baldursson, Hjalti Már Björnsson and Ari Palomäki

A comparison of two emergency medical dispatch protocols with respect to accuracy

Emergency medical dispatching should be as accurate as possible in order to ensure patient safety and optimize the use of ambulance resources. This study aimed to compare the accuracy, measured as priority lev...

Authors: Klara Torlén, Lisa Kurland, Maaret Castrén, Knut Olanders and Katarina Bohm

Proper training and use of ultrasonography facilitates lumbar puncture

With great interest, we read the study of Line Dussourd et al. concluding that ultrasonography allows better identification of anatomical structures before performing a lumbar puncture. We cannot concur with t...

Authors: Geert-Jan van Geffen, Rein Ketelaars and Jörgen Bruhn

Therapeutic hypothermia in patients with coagulopathy following severe traumatic brain injury

Coagulopathy in traumatic brain injury (TBI) has been associated with poor neurological outcomes and higher in-hospital mortality. In general principle of trauma management, hypothermia should be prevented as ...

Authors: Toru Hifumi, Yasuhiro Kuroda, Kenya Kawakita, Susumu Yamashita, Yasutaka Oda, Kenji Dohi and Tsuyoshi Maekawa

Noise exposure during prehospital emergency physicians work on Mobile Emergency Care Units and Helicopter Emergency Medical Services

Prehospital personnel are at risk of occupational hearing loss due to high noise exposure. The aim of the study was to establish an overview of noise exposure during emergency responses in Mobile Emergency Car...

Authors: Mads Christian Tofte Hansen, Jesper Hvass Schmidt, Anne C. Brøchner, Jakob Kjersgaard Johansen, Stine Zwisler and Søren Mikkelsen

Impact of systolic blood pressure limits on the diagnostic value of triage algorithms

Major incidents are characterized by a lack of resources compared to an overwhelming number of casualties, requiring a prioritization of medical treatment. Triage algorithms are an essential tool for prioritiz...

Authors: Tobias Neidel, Nicolas Salvador and Axel R. Heller

Pre-hospital advanced airway management in children: a challenge that training can handle

We respond to the Tarpgaard et al. article reporting on pre-hospital endotracheal intubation (PHETI) success and complications by Danish critical care teams including critical care anaesthetists. We compare th...

Authors: Joanna B. Watterson, Cliff Reid, Brian J. Burns and Luke Regan

The effect on the patient flow in local health care services after closing a suburban primary care emergency department: a controlled longitudinal follow-up study

It has not been studied what happens to patient flow to EDs and other parts of local health care system if distances to ED services are manipulated as a part of health policy in urban areas.

Authors: Katri Mustonen, Jarmo Kantonen and Timo Kauppila

Routine blood tests are associated with short term mortality and can improve emergency department triage: a cohort study of >12,000 patients

Prioritization of acutely ill patients in the Emergency Department remains a challenge. We aimed to evaluate whether routine blood tests can predict mortality in unselected patients in an emergency department ...

Authors: Michael Kristensen, Anne Kristine Servais Iversen, Thomas Alexander Gerds, Rebecca Østervig, Jakob Danker Linnet, Charlotte Barfod, Kai Henrik Wiborg Lange, György Sölétormos, Jakob Lundager Forberg, Jesper Eugen-Olsen, Lars Simon Rasmussen, Morten Schou, Lars Køber and Kasper Iversen

S100A8/A9 and sRAGE kinetic after polytrauma; an explorative observational study

Following tissue injury after trauma, the activation of innate immune pathways results in systemic inflammation, organ failure and an increased risk of infections. The objective of this study was to characteri...

Authors: Philippe Joly, John C. Marshall, Philippe A. Tessier, Chantal Massé, Nathalie Page, Anne Julie Frenette, François Khazoom, Soazig Le Guillan, Yves Berthiaume and Emmanuel Charbonney

Letter to the Editor regarding the article: "identifying pre-hospital factors associated with outcome for major trauma patients in a regional trauma network: an exploratory study"

The aim of this Letter to the Editor was to report some methodological shortcomings in a recently published article. Issues regarding missing values and overfitting are mentioned. First, Complete Case (CC) ana...

Authors: Charlie A. Sewalt, Eveline J. A. Wiegers, Esmee Venema and Hester F. Lingsma

Treatment of splenic trauma in Norway: a retrospective cohort study

Non-operative management of splenic injuries has become the treatment of choice in hemodynamically stable patients over the last decades. The aim of the study is to describe the incidence, initial treatment an...

Authors: Trond Dehli, Jorunn Skattum, Bjørn Christensen, Ole-Petter Vinjevoll, Bent-Åge Rolandsen, Christine Gaarder, Pål Aksel Næss and Torben Wisborg

Anaphylaxis in an emergency care setting: a one year prospective study in children and adults

Current data on anaphylaxis is based on retrospective and register based studies. The objective of this study was to describe the epidemiology of anaphylaxis in a 1 year prospective study at the emergency care...

Authors: Athamaica Ruiz Oropeza, Annmarie Lassen, Susanne Halken, Carsten Bindslev-Jensen and Charlotte G Mortz

A case of blunt thoracic aortic injury requiring ECMO for acute malperfusion before TEVAR

Blunt thoracic aortic injury (BTAI) is associated with a high mortality rate and the paradigm of treating patients with BTAI currently favours thoracic endovascular aneurysm repair (TEVAR) if possible. In BTAI...

Authors: Daiki Wada, Koichi Hayakawa, Shuji Kanayama, Shuhei Maruyama, Hiromu Iwamura, Noriyuki Miyama, Fukuki Saito, Yasushi Nakamori and Yasuyuki Kuwagata

High-performing trauma teams: frequency of behavioral markers of a shared mental model displayed by team leaders and quality of medical performance

High quality team leadership is important for the outcome of medical emergencies. However, the behavioral marker of leadership are not well defined. The present study investigated frequency of behavioral marke...

Authors: Bjørn Helge Johnsen, Heidi Kristina Westli, Roar Espevik, Torben Wisborg and Guttorm Brattebø

Low sensitivity of qSOFA, SIRS criteria and sepsis definition to identify infected patients at risk of complication in the prehospital setting and at the emergency department triage

Sepsis is defined as life-threatening organ dysfunction caused by a host response to infection. The quick SOFA (qSOFA) score has been recently proposed as a new bedside clinical score to identify patients with...

Authors: Selin Tusgul, Pierre-Nicolas Carron, Bertrand Yersin, Thierry Calandra and Fabrice Dami

Epidemiological comparison between the Navarra Major Trauma Registry and the German Trauma Registry (TR-DGU®)

International benchmarking can help identify trauma system performance issues and determine the extent to which other countries also experience these. When problems are identified, countries can look to high p...

Authors: B. Ali Ali, R. Lefering, M. Fortun Moral and T. Belzunegui Otano

Prehospital prognosis is difficult in patients with acute exacerbation of chronic obstructive pulmonary disease

Patients with acute exacerbation of chronic obstructive pulmonary disease often require prehospital emergency treatment. This enables patients who are less ill to be treated on-site and to avoid hospital admis...

Authors: Katrine P. Lindvig, Anne C. Brøchner, Annmarie T. Lassen and Søren Mikkelsen

Use of intrathoracic pressure regulation therapy in breathing patients for the treatment of hypotension secondary to trauma

Intrathoracic pressure regulation (IPR) therapy has been shown to increase blood pressure in hypotensive patients. The potential value of this therapy in patients with hypotension secondary to trauma with blee...

Authors: Victor A. Convertino, Brent A. Parquette, David A. Wampler, Craig A. Manifold, David A. Lindstrom, Lori L. Boland, Nathan T. Burkhart, Keith G. Lurie and Charles J. Lick

EMT-led laryngeal tube vs. face-mask ventilation during cardiopulmonary resuscitation - a multicenter prospective randomized trial

Laryngeal tube (LT) application by rescue personnel as an alternate airway during the early stages of out-of-hospital cardiac arrest (OHCA) is still subject of debate. We evaluated ease of handling and efficac...

Authors: Anna Fiala, Wolfgang Lederer, Agnes Neumayr, Tamara Egger, Sabrina Neururer, Ernst Toferer, Michael Baubin and Peter Paal

Erratum to: Shock in the emergency department; a 12 year population based cohort study

Authors: Jon Gitz Holler, Daniel Pilsgaard Henriksen, Søren Mikkelsen, Lars Melholt Rasmussen, Court Pedersen and Annmarie Touborg Lassen

Common intensive care scoring systems do not outperform age and glasgow coma scale score in predicting mid-term mortality in patients with spontaneous intracerebral hemorrhage treated in the intensive care unit

Intensive care scoring systems are widely used in intensive care units (ICU) around the world for case-mix adjustment in research and benchmarking. The aim of our study was to investigate the usefulness of com...

Authors: Marika Fallenius, Markus B. Skrifvars, Matti Reinikainen, Stepani Bendel and Rahul Raj

Specialist advice may improve patient selection for decompression therapy following diving accidents: a retrospective observational study

Even in a landlocked country like Switzerland recreational diving is becoming more and more popular. Smaller lakes in the Alps are located at an altitude of 2500 m above sea level. The incidence of diving acci...

Authors: Daniel Steffensmeier, Roland Albrecht, Jürg Wendling, Roger Melliger, Donat R. Spahn, Philipp Stein and Christophe Wyss

Post-trauma morbidity, measured as sick leave, is substantial and influenced by factors unrelated to injury: a retrospective matched observational cohort study

Mortality as an endpoint has been the focus of trauma research whereas few studies investigate long-term outcomes in terms of morbidity. An adequate analysis of post-injury morbidity includes several dimension...

Authors: Erik von Oelreich, Mikael Eriksson, Olof Brattström, Andrea Discacciati, Lovisa Strömmer, Anders Oldner and Emma Larsson

The impact of early thromboelastography directed therapy in trauma resuscitation

Conventional coagulation tests do not provide an accurate representation of the complex nature of trauma induced coagulopathy. Thrombelastography provides a prompt global overview of all dynamic sequential asp...

Authors: Mohamed Mohamed, Karl Majeske, Gul R. Sachwani, Kristin Kennedy, Mina Salib and Michael McCann

Intoxication with GHB/GBL: characteristics and trends from ambulance-attended overdoses

Overdoses from so-called “club drugs” (GHB/GBL) have become a more frequent cause of overdoses attended by ambulance services. Given its availability, affordability, and lack of awareness of risks, there is a ...

Authors: Desiree Madah-Amiri, Lars Myrmel and Guttorm Brattebø

Factors influencing on-scene time in a rural Norwegian helicopter emergency medical service: a retrospective observational study

Critically ill patients need to be immediately identified, properly managed, and rapidly transported to definitive care. Extensive prehospital times may increase mortality in selected patient groups. The on-sc...

Authors: Øyvind Østerås, Jon-Kenneth Heltne, Bjørn-Christian Vikenes, Jörg Assmus and Guttorm Brattebø

Barriers and facilitators towards implementing the Sepsis Six care bundle (BLISS-1): a mixed methods investigation using the theoretical domains framework

The ‘Sepsis 6’, a care bundle of basic, but vital, measures (e.g. intravenous fluid, antibiotics) has been implemented to improve sepsis treatment. However, uptake has been variable. Tools from behavioral scie...

Authors: Neil Roberts, Guy Hooper, Fabiana Lorencatto, Wendell Storr and Michael Spivey

Neurological outcomes and duration from cardiac arrest to the initiation of extracorporeal membrane oxygenation in patients with out-of-hospital cardiac arrest: a retrospective study

We investigated the relationship between neurological outcomes and duration from cardiac arrest (CA) to the initiation of extracorporeal membrane oxygenation (ECMO) (CA-to-ECMO) in patients with out-of-hospita...

Authors: Takahiro Yukawa, Masahiro Kashiura, Kazuhiro Sugiyama, Takahiro Tanabe and Yuichi Hamabe

Physician-staffed helicopter emergency medical service has a beneficial impact on the incidence of prehospital hypoxia and secured airways on patients with severe traumatic brain injury

After traumatic brain injury (TBI), hypotension, hypoxia and hypercapnia have been shown to result in secondary brain injury that can lead to increased mortality and disability. Effective prehospital assessmen...

Authors: Toni Pakkanen, Antti Kämäräinen, Heini Huhtala, Tom Silfvast, Jouni Nurmi, Ilkka Virkkunen and Arvi Yli-Hankala

The effect of a national web course “Help-Brain-Heart” as a supplemental learning tool before CPR training: a cluster randomised trial

The effectiveness of cardiopulmonary resuscitation (CPR) learning methods is unclear. Our aim was to evaluate whether a web course before CPR training, teaching the importance of recognition of symptoms of str...

Authors: Anette Nord, Leif Svensson, Andreas Claesson, Johan Herlitz, Håkan Hult, Susanne Kreitz-Sandberg and Lennart Nilsson