Table 1 Description of included studies
Study ID | Country | Language | Study design | Recruitment Dates | Excluded Heart Disease | Total Patients | Age (years) Mean (SD) | Prevalence Disease | Target Condition | Reference Standard |
|---|---|---|---|---|---|---|---|---|---|---|
Ahn [30] | Korea | English | Cohort study | Jan 2011–Dec 2011 | No | 308 | 67.7 (19.1) | 22.1% | ACS | Final diagnosis |
Allen [56] | United States | English | Cohort study | NA | No | 178 | 59 (NA) | 3.9% | MI | Not reported |
Atar [76] | Israel | English | Cohort study | NA | No | 70 | 50 (12) | 14.3% | ACS | Chart Review |
Bracey [28] | United States | English | Cohort study | NA | NR | 16 | 61 (15.2) | 81.3% | Significant Coronary Stenosis | Coronary Angiography |
Castini [27] | Italy | Italian | Cohort study | NA | Yes | 22 | 63 (9) | 31.8% | Myocardial Infarction | Combination of Tests |
Cevrim [57] | Turkey | English | Cohort study | Jun 2011–Dec 2011 | Yes | 48 | 49 (13) | 8.3% | ACS | Final diagnosis |
Chandra [77] | United States | English | Cohort study | Dec 2014 | No | 26 | NA | 15.4% | ACS | Chart Review |
Dahlslett [58] | Norway | English | Cohort study | NA | Yes | 64 | CAD + : 54 (12) CAD-: 56 (12) | 45.3% | Significant Coronary Stenosis | Coronary Angiography |
DeLoizaga [59] | United States | English | Cohort study | Dec 2012–Nov 2013 | Yes | 80 | 56 (13) | 10.0% | ACS | Chart Review |
DiPasquale [23] | Italy | English | Cohort study | Dec 2000–Feb 2002 | Yes | 280 | 59.7 (11.9) | 65.0% | Significant Coronary Stenosis | Coronary Angiography |
Hickman [61] | UK | English | Cohort study | NA | No | 80 | 64 (13.5) | 16.3% | MI | Cardiac Enzymes |
Kang [62] | Korea | English | Cohort study | Oct 2001–Dec 2002 | Yes | 114 | 60 (10) | 76.3% | ACS | Combination of Tests |
Kontos [63] | United States | English | Cohort study | Aug 1994–Dec 1994 | No | 260 | 54 (14) | 17.3% | MI | Combination of Tests |
Korosoglou [64] | Germany | English | Cohort study | NA | Yes | 98 | ACS + : 65 (12) ACS-: 57 (15) | 37.8% | ACS | Chart Review by Independent person |
Kountana [65] | Greece | English | Cohort study | Mar 2010–Dec 2011 | No | 33 | 59.8 (10.8) | 15.2% | ACS | Combination of Tests |
Lee [66] | Korea | English | Cohort study | Jan 2011–Dec 2011 | Yes | 69 | 55 (14) | 36.2% | Significant Coronary Stenosis | Coronary Angiography |
Mahmoud [24] | Saudi Arabia | English | Cohort study | Aug 2014–Oct 2016 | No | 250 | 67 (2.4) | 53.2% | ACS | Chart Review |
Mohler [29] | United States | English | Cohort study | NA | No | 100 | 55.6 (12) | 59.8% | ACS | Chart Review |
Oh [67] | United States | English | Cohort study | NA | Yes | 26 | 58 (NA) | 26.9% | MI | Combination of Tests |
Onishi [68] | Japan | English | Cohort study | NA | NR | 91 | NA | 50.5% | ACS | Coronary Angiography |
Peels [69] | Netherlands | English | Cohort study | Dec 1987–Nov 1988 | Yes | 43 | 54 (NA) | 58.1% | Significant Coronary Stenosis | Coronary Angiography |
Sabia [70] | United States | English | Cohort study | Apr 1987–Jun 1987 | No | 180 | 62 (14) | 17.2% | MI | Cardiac Enzymes |
Santana [26] | Brazil | Portuguese | Cohort study | Jun 2006–Jun 2008 | NR | 71 | 56 (NA) | 30.6% | ACS | Final diagnosis |
Sasaki [25] | United States | English | Cohort study | NA | Yes | 46 | 60 (11) | 50.0% | ACS | Combination of Tests |
Shiran [71] | Israel | English | Cohort study | NA | Yes | 605 | 58 v | 12.2% | ACS | Final diagnosis |
Sobczyk [72] | Poland | English | Cohort study | Jan 2013–Jan 2014 | No | 1312 | 67 (12.3) | 79.2% | MI | Chart Review |
Swinburn [73] | United Kingdom | English | Cohort study | NA | No | 80 | 64 (13.5) | 15.0% | MI | Combination of Tests |
Weston [74] | United States | English | Cohort study | NA | No | 108 | HHE + : 58 (13), HHE -: 52 (12) | 11.1% | ACS | Combination of Tests |
Wilben [75] | India | English | Cross sectional study | Nov 2017–Oct 2019 | Yes | 385 | 55.1 (14.2) | 81.0% | ACS | Coronary Angiography |