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Table 1 Articles included for analysis

From: Suspension syndrome: a scoping review and recommendations from the International Commission for Mountain Emergency Medicine (ICAR MEDCOM)

Author

Year

Study design

Sample Size

Key findings

Quality assessment

Patscheider [6]

1972

Observational autopsy study

5 (climbers died in the Tyrolean alps between 1957 – 1968)

Hypoxic changes of heart, liver and in one case kidney

Protracted orthostatic shock is the cause of organ injury

Fair

Flora et al. [15]

1972

Summary of results from physiological experimental human studies with chest harness suspension presented at the 2nd international Conference of Mountain Rescue physicians (original articles are not available)

 

Massive circulatory obstruction

Increase of heart rate and reduction of pulse pressure

Reduction of blood pressure

Drop of central venous pressure

Reduction of renal function

ECG changes

Presyncopal syndroms in subjects

Poor

Flora et al. [2]

1972

Case series with pathophysiologic parameters

23 (10 died, 13 survived)

Reported pathophysiological conditions: acute kidney injury, hypoxic heart muscle damage, muscle necrosis and dyspnoea

Arm plexus damage in chest harness after 10 to 20 min of free suspension, if no foot loops were used

Death occurred regularly after suspension longer than two hours

Fair

Stuehlinger et al. [24]

1972

Observational physiologic human study

10, two trial runs

Hanging in a chest harness was aborted after 8 to 22 min due to pallor, cold sweat, nausea and paraesthesia in the upper extremities

Hanging in a sit harness was aborted in 3 cases after 22 to 28 min due to clinical symptoms

Tachycardia and hypertension due to sympathetic activation

Indirect signs of peripheral blood pooling

Sinus arrythmia and extrasystoles after placement in horizontal position after trial, which led to the assumption of sudden cardiac arrest due to horizontal placement after hanging

Glomerular filtration and renal plasma flow drops already after only 8 min, with further drop while hanging

Fair

Orzech et al. [25]

1987

Observational physiologic human study and review

13 (each with body belt, chest harness, full body harness)

Suspension tolerance in a body belt or chest harness alone is significantly lower than in a full body harness, due to pain and difficulty of breathing during hanging

Fair

Roeggla et al. [26]

1996

Observational physiologic human study

6 (each with chest harness alone or sit harness)

Decrease of vital capacity, forced expiratory volume and cardiac output in chest harness suspension

Good

Madsen et al. [27]

1998

Observational physiologic human study

9 knee strap suspension

79 50° head up tilt table

11% developed symptoms with knee strap, 87% developed symptoms with 50° head up tilt

Longer tolerance of suspension with support strap under knees due to preserved venous return

Initial heart rate and blood pressure increase followed by a drop with onset of presyncopal symptoms

Reduction of central blood volume during head up tilt

Fair

Shamsuzzaman et al. [28]

1998

Observational physiologic human study

13 (each on tilt table and tilted suspension)

One vasovagal reaction during “suspension”

Engagement of antigravity muscles have effects on sympathetic vasoconstriction and cardiovascular responses

During suspension reduction of cardiac output and stroke volume, tachycardia and hypertension

Good

Rollnik et al. [29]

2001

Observational physiologic human study

14

Suspension in supine position (one sling around the thorax and one sling around the thighs) caused only moderate heart rate changes, which were significantly lower compared to vertical suspension

Vertical suspension with a sling placed under the armpits was tolerated only 2—4 min

Fair

Seddon et al. [4]

2002

National survey

Not applicable

No suspension syndrome within 5.8 million on-rope hours by rope access technicians qualified by IRATA (International Rope Access Trade Association)

Fair

Pisati et al. [30]

2007

Case report with discussion of pathophysiologic parameters

2

Prolonged hanging in a sit harness caused pulmonary thrombo-embolism and thrombosis of femoral artery, most likely due to compression by harness groin straps

Poor

Turner et al. [31]

2008

Observational physiologic human study

40 (each on front and back attachment)

28 (harness with leg support for a more horizontal suspension position)

Harness with leg support doubled suspension time

Body weight reduced suspension time with back attachment

Good

Ruhrmann et al. [32]

2010

National survey among height rescue organizations

68 questionnaires

3 cases of suspension syndrome in 131 datasets

Poor

Wharton et al. [7]

2011

Case report with pathophysiologic parameters

1

Suspension > 4 h

Rhabdomyolysis and acute kidney injruy

Poor

Hsiao et al. [33]

2012

Observational physiologic human study

37

Suspension tolerance between 5 and 56 min

Static harness fit does not correlate with suspension tolerance

Improperly conformed / sized harness could increase risk of suspension syndrome

Rear attachment with angle > 35° between torso and suspension line has shorter suspension time

Good

Hsiao et al. [34]

2013

Observational physiologic human study and Fourier analysis of torso scans

216

different harness sizes are necessary for optimal fit

Harness fit is partly dependent on gender

Harness adjustment is necessary for clothing and other equipment

Good

Goossens et al. [35]

2014

Case report

1

Combination of heat stroke and suspension syndrome after 1 h of suspension

Unconsciousness, rhabdomyolysis, and acute kidney injury

Poor

Lanfranconi et al. [10]

2017

Observational physiologic human study

40

Syncope in 10% with drop of systolic blood pressure, tachycardia just before syncope and bradycardia during recovery

Onset of syncope from aprupt to minutes after first clinical signs

Decrease of cerebral oxygenated hemoglobin before syncope

Good

Beverly et al. [36]

2019

Observational physiologic human study

18, with two trial runs

Tolerance of rear attachment hanging is significantly lower than front attachment (shorter duration of hanging, more trial terminations)

25% suffered symptoms which lead to trial termination, one near syncope

Bradycardia in three subjects who terminated trial early

Weak laboratory signs of muscle damage with dorsal attachment (significant aspartate aminotransferase increase)

Fair

Lanfranconi et al. [37]

2019

Observational physiologic human study

40

Syncope in 10% with decrease of arterial oxygen saturation and a drop of systolic blood pressure

Short suspension tolerance participants (no syncope) had a changed of breathing pattern (increase of tidal volume, decrease of frequency, increase in respiratory elastic power) stress induced hypertension (sympathetic activation)

Good

Rauch et al. [11]

2019

Observational physiologic human study

20

Sudden pre-syncope in 30%

Vagal mechanism leads to loss of consciousness (bradycardia and drop in systolic blood pressure)

Time to pre-syncope is unpredictable

Good

Rauch et al. [38]

2019

Observational physiologic human study

20

Free hanging leads to rapid venous pooling in the limbs

Most important preventive measure might be constant leg movement

Pulmonary embolism might be preventable cause of death

Good

Baszczynski [39]

2022

Observational manikin study

4 industrial climbing harnesses

Industrial climbing harnesses, especially with rear attachment, have a high risk of excessive local pressure

Poor