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Table 4 Results of the prospective randomized controlled study 8

From: Frostbite treatment: a systematic review with meta-analyses

The prospective randomized controlled study by Cauchy et al. 8

   

Treatment

Cases

Digit salvage rate

p-value

Buflomedil + ASA

15

60%

 

Buflomedil + Iloprost + ASA

16

100%

 < 0.001

Buflomedil + tPA + Iloprost + ASA

16

97%

 < 0.03

  1. The p-value refers to the comparison with the Buflomedil alone group by Fisher’s exact test. tPA = Tissue plasminogen activator, ASA = Acetylsalicylic acid