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Table 3 Final multivariate model-Adjusted association of variables with hypotension (defined as a new SBP < 90 mmHg ≤ 10 min of induction, or a > 10% drop if SBP was < 90 mmHg pre-PHEA) for adult trauma patients who underwent PHEA in the East of England, 2015–2020

From: Predictors of post-intubation hypotension in trauma patients following prehospital emergency anaesthesia: a multi-centre observational study

Variable

Adjusted Odds ratio (95% CI)

P-value

Age/years

 16–34

REF

 

 35–54

1.23 (0.81–1.86)

0.324

 55–74

2.13 (1.38–3.29)

< 0.001***

 75 +

1.90 (1.08–3.31)

0.024 *

Pre-PHEA SBP/mmHg

 Mid (90–140)

REF

 

 Low < 90)

0.71 (0.43–1.15)

0.174

 High (> 140)

0.37 (0.25–0.54)

< 0.001***

Pre-PHEA HR/beats/minute

 Mid (60–100)

REF

 

 Low (< 60)

1.43 (0.76–2.59)

0.256

 High (> 100)

1.81 (1.28–2.57)

< 0.001***

RSI drug regime (fentanyl:ketamine:rocuronium)

 3:2:1

REF

 

 1:1:1

1.12 (0.68–1.83)

0.662

 0:1:1

2.09 (1.29–3.41)

0.003**

 0:0:1 (Roc only)

2.86 (1.34–6.09)

0.006**

 Other

1.35 (0.81–2.24)

0.245

Pre-PHEA fluids

 None

REF

 

 Fluids

1.59 (1.13–2.23)

0.007**

Suspected injury pattern

 Isolated head injury

REF

 

 Head injury + thorax/abdomen

1.63 (1.13–2.36)

0.009**

 No head injury

1.32 (0.80–2.15)

0.277

  1. *P < 0.05, **P < 0.01, ***P < 0.001
  2. PHEA prehospital emergency anaesthetic, RSI rapid sequence induction, HR heart rate, SBP systolic blood pressure, RR respiratory rate
  3. Pre-PHEA fluids are intravenous crystalloid administration by the ambulance service before arrival of HEMS