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Box 1 Description of included scores

From: External validation of the PROLOGUE score to predict neurological outcome in adult patients after cardiac arrest: a prospective cohort study

Score

Outcome predicted

Variables

Score calculation

OHCA

Poor neurological outcome (CPC 3–5)

Initial rhythm: VF or VT [yes/no]

−13 if no

No-flow interval [min]

+ 6 × ln(no-flow interval)

Low-flow interval [min]

+ 9 × ln(low-flow interval)

Serum creatinine [µmol/L]

−1434/(serum creatinine)

Arterial lactate [mmol/L]

 + 10 × ln(arterial lactate)

CAHP

Poor neurological outcome (CPC 3–5)

Age [years]

Points attributed by nomogram for all variables

Arrest setting [home/public]

Shockable rhythm [yes/no]

No-flow interval [min]

Low-flow interval [min]

pH at admission

Dosage of epinephrine administered [0, 1–2 or ≥ 3 mg]

PROLOGUE

Poor neurological outcome (CPC 3–5)

Unwitnessed collapse

Points attributed by nomogram for all variables

Potassium ≥ 4.4 mEq/L

Lactate ≥ 8 mmol/l

Adrenaline dose ≥ 2 mg

Low-flow duration ≥ 18 min

Haemoglobin < 13.2 g/dl

Creatinine ≥ 1.21 mg/dl

Phosphate ≥ 5.8 mg/dl

Non-shockable rhythm

Absent pupillary light reflex

Age ≥ 59 years

Glasgow Coma Scale motor score < 2

  1. CAHP Cardiac arrest hospital prognosis score, CPC Cerebral performance category scale, ln logarithmus naturalis, OHCA out-of-hospital cardiac arrest score, PROLOGUE prognostication using logistic regression model for unselected adult cardiac arrest patients in the early stages, VF ventricular fibrillation, VT ventricular tachycardia