Diagnostic performance of Glial Fibrillary Acidic Protein and Prehospital Stroke Scale for identification of stroke and stroke subtypes in an unselected patient cohort with symptom onset < 4.5 h

Table 2 AUCs of GFAP and PreSS for identification of stroke, ICrH, and LVO

	GFAP		PreSS part 1		PreSS part 2		GFAP and PreSS^a
	Apparent AUC	Cross fold validated AUC	Apparent AUC	Cross fold validated AUC	Apparent AUC	Cross fold validated AUC	Apparent AUC	Cross fold validated AUC
Stroke and TIA	0.62 (0.56–0.69)	0.54 (0.47–0.60)	0.66 (0.60–0.72)	0.64 (0.58–0.71)	n/a	n/a	0.65 (0.58–0.71)	0.65 (0.59–0.71)
ICrH	0.79 (0.69–0.89)	0.73 (0.62–0.84)	0.71 (0.61–0.81)	0.69 (0.58–0.80)	0.71 (0.62–0.81)	0.66 (0.57–0.79)	0.80 (0.71–0.90)	0.71 (0.59–0.83)
LVO	0.44 (0.32–0.55)	0.35 (0.23–0.46)	0.76 (0.66–0.85)	0.72 (0.62–0.82)	0.69 (0.58–0.81)	0.66 (0.54–0.78)	0.71 (0.60–0.82)	0.67 (0.55–0.79)

AUC area under the receiver-operating characteristics curve, GFAP glial fibrillary acidic protein, ICrH intracranial hemorrhage, LVO large-vessel occlusion, PreSS Prehospital Stroke Score, TIA transient ischemic attack
^aGFAP combined with: PreSS part 1 to identify stroke and TIA; PreSS part 1 and 2 to identify ICrH; and PreSS part 2 to identify LVO
Numbers in parentheses = 95% confidence interval

ISSN: 1757-7241