Ketamine versus propofol for rapid sequence induction in trauma patients: a retrospective study

Table 3 Multivariable linear regression analyses of secondary outcomes for intubated trauma patients

	P-value for hospital LOS	P-value for ICU LOS	P-value for duration of mechanical ventilation
Ketamine versus propofol (reference) primary analyses (N = 548)	0.43	0.68	1.00
Sex, male	0.54	0.85	0.99
Age	0.007*	0.27	0.99
ISS	0.85	0.0003*	1.00
SBP before intubation < 90 mmHg	0.88	0.97	1.00
GCS before intubation	< 0.001*	0.45	0.99
Ketamine versus propofol (reference) secondary analyses (N = 510)	0.67	0.89	0.79
Sex, male	0.34	0.29	0.58
Age	0.005*	0.003*	0.04*
ISS	0.039*	0.002*	0.2
SBP before intubation < 90 mmHg	0.59	0.22	0.94
GCS before intubation	0.24	0.1	0.07

Multivariable linear regression analyses of secondary outcomes (hospital length of stay, ICU length of stay and duration of mechanical ventilation) for the primary (N = 548) and secondary analyses (N = 510) presented as P-values adjusted for sex, age, ISS, SBP and GCS before intubation. In the secondary analysis we excluded patients if both ketamine and propofol had been used within approximately 15 min prior to emergency intubation, and it was unclear which one had been used as induction agent
GCS Glasgow Coma Scale, ICU Intensive Care Unit, ISS Injury Severity Score, LOS Length of Stay, SBP Systolic Blood Pressure
*Statistically significant: P < 0.05

ISSN: 1757-7241