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Table 5 Demographics, pre-hospital time, systolic blood pressure (SBP; pre-hospital and on admission), Glasgow Coma Scale (GCS; pre-hospital and on admission), selected pre-hospital therapeutic interventions, Injury Severity Score (ISS), Abbreviated Injury Scale (AIS) and selected laboratory values of patients with TBI and hypotension on hospital admission (group1), subdivided between patients intubated and not intubated on scene

From: Severe traumatic brain injury and hypotension is a frequent and lethal combination in multiple trauma patients in mountain areas – an analysis of the prospective international Alpine Trauma Registry

Parameter

TBI with hypotension

(n = 50)

Pre-hospital intubation

 

Yes

No

p-value

Age, years, mean ± SD

42.7 ± 19.6

49.4 ± 18.6

0.243

Female sex, n (%)

7 (32%)

9 (32%)

1.000

Pre-hospital SBP, mmHg, mean ± SD

102.0 ± 22.8

103.8 ± 29.3

0.844

SBP on hospital arrival, mmHg, mean ± SD

81.1 ± 12.2

84.8 ± 13.4

0.325

Pre-hospital GCS, mean ± SD

5.8 ± 3.

11.8 ± 3.2

< 0.001

GCS on hospital arrival, mean ± SD

3.3 ± 1.3

12.0 ± 3.5

< 0.001

Crystalloid fluids, ml, mean ± SD

636 ± 303

821 ± 346

0.194

Vasopressor therapy, n (%)

1 (7%)

3 (16%)

0.613

Total pre-hospital time, min, median (range)

82 (33–221)

82.5 (30–1560)

0.881

ISS, mean ± SD

41.1 ± 13.3

44.6 ± 20.2

0.930

AIS head and neck

3.9 ± 0.9

4.5 ± 1.1

0.054

AIS face

2.5 ± 0.7

4.0 ± 1.2

0.133

AIS thorax

3.8 ± 0.8

3.7 ± 0.9

0.846

AIS abdomen

3.2 ± 0.9

3.6 ± 1.1

0.467

AIS extremities

3.7 ± 0.9

3.6 ± 1.1

0.752

AIS external

3a

Hemoglobin, g/dl

11.3 ± 2.7

10.4 ± 2.8

0.221

INR

1.4 ± 0.6

1.7 ± 0.7

0.254

aPTT, sec

34.3 ± 21.6

54.7 ± 48.6

0.135

Base excess

−6.3 ± 5.1

−4.6 ± 7.7

0.377

  1. Tests performed were independent samples t-tests, except for pre-hospital GCS and GCS on hospital arrival, crystalloid fluids, total pre-hospital time, ISS and AIS head/neck, for which Mann-Whitney U test was used and for vasopressor therapy and female sex, for which Fisher’s exact test was applied
  2. INR international normalized ratio
  3. aonly one case, aPTT activated partial thromboplastin time