Skip to main content

Table 5 Study variables positively and negatively correlated with SARS-COV-2 positivity

From: Development of machine learning models to predict RT-PCR results for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in patients with influenza-like symptoms using only basic clinical data

Positive linear correlation
VARIABLES Pearson R VARIABLES Pearson R
*Fever 0.33 *Sinus Rhythm 0.06
*Body temperature (degree Celsius) 0.27 *Chronic kidney disease 0.05
Lymphocytes percentage 0.26 *Monocytes percentage 0.05
Cough 0.22 Hypertension 0.04
*Total red blood cells count (106/μL) 0.19 Asthma 0.04
*Haemoglobin (g/dL) 0.17 *Age 0.04
Glasgow coma scale (GCS) 0.17 Gastrointestinal symptoms 0.04
*Antibiotics before Emergency Department 0.16 *Calcium channel antagonist 0.04
*Chest pain 0.15 Mean corpuscular haemoglobin concentration (%) 0.03
*Chest X-rays opacity 0.14 Respiratory rate (breaths/min) 0.03
*Sartans 0.13 *Female 0.02
*Systolic blood pressure (mmHg) 0.12 *Headache 0.02
Haematocrit (%) 0.12 *Immunosuppressant drugs 0.02
Arthralgia 0.09 *Hydroxymethylglutaryl-CoA (HMG-CoA)
reductase inhibitors
0.02
*Diastolic blood pressure (mmHg) 0.07 Hematologic malignancy 0.02
P wave present and normal 0.07 *Angiotensin converting enzyme inhibitor 0.01
*5-alpha-reductase inhibitors 0.07 Heart rate (beats per minute) 0.00
Chronic Interstitial lung disease 0.06   
Negative linear correlation
VARIABLES Pearson R VARIABLES Pearson R
*Total white blood cells count (103/μL) −0.46 *Dyspnoea −0.07
*Eosinophils percentages −0.34 *Ischemic cardiomyopathy −0.06
Platelets (103/μL) − 0.33 *Basophils percentage − 0.06
*Anti-epileptic therapy −0.25 Diabetes mellitus −0.06
*Calcium (mg/dL) −0.22 Creatinine (mg/dL) −0.06
Mean red blood cell volume (μm3) −0.21 *Mean corpuscular haemoglobin (pg) −0.06
Neutrophils percentages −0.19 *Non Invasive Ventilation −0.05
*Drugs for psychiatric disorders −0.19 Autoimmune/inflammatory disease −0.04
*Chest X-rays pleural effusion −0.19 Red blood cells distribution width (%) −0.04
*Chronic obstructive pulmonary disease −0.17 Anti-arrhythmic drugs −0.04
*Smoking (active) −0.15 Syncope −0.04
*Urea (mg/dL) −0.14 Glycaemia (mg/dL) −0.03
*Total bilirubin (mg/dL) −0.14 *Diuretics −0.03
Oxygen supplementation −0.11 Atrial fibrillation −0.03
*Solid organ tumour −0.11 C-reactive protein (mg/dL) −0.03
*Sore throat −0.10 *Male −0.02
Human Immunodeficiency Virus −0.09 Beta blocker −0.02
Asthenia −0.08 Anticoagulant therapy −0.02
Chronic liver disease −0.08 *Anti-platelets therapy −0.02
*Sodium (mEq/L) −0.07   
  1. Variables were divided according to their positive or negative correlation to the target variable (positivity of RT-PCR for SARS-COV-2) and are listed in decreasing order of positive or negative correlation coefficient, respectively. Asterisks indicate variables included in the TWIST model