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Table 2 Compiled human data from 52 papers selected from literature review

From: Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA): update and insights into current practices and future directions for research and implementation

Setting Author, Year, N Age/Sex Injury Zone Duration (min) Survival(%)
P B O I II III
OOH Military Manley, 2017, 4 [14] NR/4 M 4    3   1 35 100
Lyon, 2018, 1 [15] 25/M 1    1    34 100
Northern, 2018, 20 [16] 18–30/NR 20    17   3 21 100
de Schoutheete, 2018, 3 [17] 39.7/2 M, 1F 3    3    31.3 100
Civilian Sadek, 2016, 1 [18] 32/M   1     1 NR 100
Rich, 2017, 1 [19] 23/F   1     1 NR 100
Lamhaut, 2018, 1 [20] 49/F   1   1    36 100
Lendrum, 2019, 13 [21] 32/3 M, 10F   13     13 80* 62
Hospital ED Okada, 2016, 1 [22] 16/M   1   1    25 100
Teeter, 2016, 33 [23] 50/23 M, 10F 2 31   33    49†, 80‡ 421
Tsurukiri, 2016, 25 [24] 69*/15 M, 10F 1 15 9 16 5 4 61 482
Conti, 2017, 1 [25] 40/M   1     1 110 100
Maruhasi, 2017, 1 [26] 50/F   1     1 18 100
Qazi, 2017, 1 [27] 79/F   1     1 NR D
Cheema, 2018, 1 [28] Mid-50s/F   1     1 32 100
Sato, 2018, 24 [29] 52*/17 M, 7F 1 23   24    65* 41.7
Shoji, 2018, 10 [30] 58*/6 M, 4F 3 1 6 10    NR 601
Ozkurtul, 2019, 1 [31] 17/F   1     1 NR D
Shinjo, 2019, 1 [32] 75/M   1     1 NR 100
Duchesne, 2020, 524 [33] 40*/387 M, 137F 108 405 3 359 11 151 19* 49
OR Ledgerwood, 1976, 40 [2] 32/34 M, 6F 38 2   NR 27†§ 27.5   
Davidson, 2016, 1 [34] 28/M 1    1    20 100
Matsumoto, 2016, 1 [35] 37/M   1   1    25 100
Ibrahim, 2017, 1 [36] 60/M   1   1    30 + 16 100
Nilsson, 2017, 1 [37] 17/M   1     1 46 100
Rosenthal, 2018, 1 [38] 19/M   1   1    NR D
Berg, 2019, 1 [39] 14/M    1    1 NR 100
Khan, 2019, 1 [40] Mid-20s/M 1    1    < 50 D
Paradis, 2019, 1 [41] 61/M   1     1 36 1001
Samlowski, 2019, 1 [42] 53/M    1 1    47 100
Ordonez, 2020, 56 [43] 32*^, 39*°/48 M, 8F 37 19   56   (27) 40* 71.4
Other Brenner, 2013, 6 [44] 39.5/5 M, 1F 2 4   3   3 18 66.7
Saito, 2015, 24 [45] NR/NR NR 24    21S, 35 N 29.2   
Horer, 2016, 3 [46] 49.7/2 M, 1F NR 2   1 > 20§ 66.7   
Uchino, 2016, 1 [47] 86/F   1     1 NR D
Bogert, 2017, 1 [48] 24/M   1   1    NR 100
Bunya, 2017, 1 [49] 54/M   1   1    186 100
Norii, 2017, 54 [50] 18/32 M, 22FF 3 51   NR NR 42.6   
Ogura, 2017, 34 [51] 67.5*/22 M, 12F   34   NR NR 53   
Brenner, 2018, 79 [52] 40/66 M, 13F 24 54   64   15 53 44
Darrable, 2018, 16 [53] 48.7/14 M, 2F 2 11 3 16    NR 32.2
Goodenough, 2018, 1 [54] 83/M    1 1    NR 100
Matsumura, 2018, 109 [55] 60*/71 M, 38F 5 104   NR 63* 551   
Otsuka, 2018, 15 [56] 52.7/11 M, 4F   15   15    32.5 60
Pieper, 2018, 32 [57] 46*/23 M, 9F   32     32 55* 413
Singh, 2019, 2 [58] 73.5/2 M    1 NR NR 50   
Zhang, 2019, 1 [59] 72/M    1 1    > 140 D
Aoki, 2020, 633 [60] 54*/419 M, 214F 46 587   NR NR 52   
Garcia, 2020, 28 [61] 32*/22 M, 6F 28    28   (11) 41 82.1
Matsumoto, 2020, 38 [62] 42*/27 M, 11F 3 35   29 8 1 NR 42.1
Nagashima, 2020, 1 [63] 48/F   1   1    NR 100
Totals OOH 44   2863.6% 1636.4% 00% 25 56.8% 00% 19 43.2% 39.6 88.6a!
Hospital 1,807   30517.2% 143981.3% 251.4% 691 38.2% 241.3% 217 12% 50.1 50.4b!
All 1851   33318.4% 145580.3% 251.3% 716 38.7% 241.3% 226 12.2%   
  1. OOH Outside of Hospital, ED Emergency Department, OR Operating Room, NR Not Reported, P Penetrating Injury, B Blunt Injury, O Other Injury, D Deceased
  2. “Survival” indicates mixed categories of outcome, including: survival of procedure, survival to next level of care, survival to discharge. Values in parentheses indicate final location for balloon placement after initial placement in a different zone
  3. *Denotes median value (all other values are means) †Denotes value from ‘survivors’ group ‡Denotes value from ‘non-survivors’ group §Denotes value with reduced N-value ^Denotes value for ‘penetrating’ injury group °Denotes value for ‘blunt’ injury group 1 at 30-day follow-up 2 at 60-day follow-up 3 at 28-day follow-up
  4. aValue is percentage of 44 patients in OOH group that survived
  5. bValue is percentage of 1807 patients in Hospital group that survived
  6. !Significant difference, p < .0001, significance via Chi Square Test