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Table 1 Demographic and clinical characteristics

From: High HbA1c is associated with decreased 6-month survival and poor outcomes after out-of-hospital cardiac arrest: a retrospective cohort study

  Total
(n = 302)
HbA1c ≤6%
(n = 200)
HbA1c > 6%
(n = 102)
p
Demographic characteristics
 Male, n (%) 207 (68.5) 139 (69.5) 68 (66.7) 0.62
 Age, years, median (IQR) 61 (49–72) 57.0 (45–70) 67.5 (56–75) < 0.001
Underlying disease, n (%)
 Acute myocardial infarction 17 (5.6) 9 (4.5) 8 (7.8) 0.23
 Previous cardiac arrest 1 (0.3) 1 (0.5) 0 (0.0) 1.00
 Angina 34 (11.3) 20 (10.0) 14 (13.7) 0.34
 Congestive heart failure 20 (6.6) 9 (4.5) 11 (10.8) 0.05
 Hypertension 123 (40.7) 64 (32.0) 59 (57.8) < 0.001
 Cerebrovascular accident 23 (7.6) 9 (4.5) 14 (13.7) 0.004
 Diabetes mellitus 75 (24.8) 17 (8.5) 58 (56.9) < 0.001
 Lung disease 29 (9.6) 20 (10.0) 9 (8.8) 0.84
 Neurological disease 21 (7.0) 12 (6.0) 9 (8.8) 0.35
 Renal disease 27 (8.9) 12 (6.0) 15 (14.7) 0.02
 Liver cirrhosis 5 (1.7) 4 (2.0) 1 (1.0) 0.67
 Malignancy 17 (5.6) 12 (6.0) 5 (4.9) 0.80
Cardiac arrest characteristics
 Shockable rhythm, n (%) 199 (65.9) 127 (63.5) 72 (70.6) 0.25
 Witnessed arrest, n (%) 114 (37.7) 81 (40.5) 33 (32.4) 0.21
 Bystander CPR, n (%) 147 (48.7) 101 (50.5) 46 (45.1) 0.40
 Anoxic time, min, median (IQR) 30 (17–42) 30 (17–43) 30 (17–40) 0.88
Glucose-related variables
 Initial glucose level, mg/dL, median (IQR) 240 (70–521) 227 (72–414) 274 (70–648) < 0.001
 Glucose level variability within 48 h, Δ glucose, median (IQR) 140 (90–208)
(n = 237)
135 (81.5–187)
(n = 164)
154 (120.8–249.8)
(n = 73)
0.004
  1. Continuous variables are expressed as medians (interquartile ranges). HbA1c glycated hemoglobin, IQR interquartile range, CPR cardiopulmonary resuscitation, ROSC return of spontaneous circulation, S100B calcium-binding protein B