Table 4 Comparison of outcome measurements between RETTS-a combined Red/Orange level and NEWS medium/high and NEWS medium/high

Time-sensitive condition

n = 473

Se

0.732

0.370

0.345

[0.679,0.782]^b

[0.313,0.429]

[0.290,0.402]

Sp

0.540

0.789

0.833

[0.519,0.560]

[0.772,0.805]

[0.818,0.848]

PPV

0.158

0.172

0.197

[0.139,0.179]

[0.141,0.203]

[0.161,0.232]

NPV

0.944

0.914

0.915

[0.932,0.956]

[0.900,0.926]

[0.902,0.927]

ACC

0.560

0.744

0.781

[0.541,0.579]

[0.727,0.761]

[0.765,0.797]

AUROC^c

0.636

0.579

0.589

[0.607,0.662]

[0.549,0.609]

[0.560,0.619]

Deviating VS/complication within 48 h

n = 455

Se

0.908

0.774

0.636

[0.870,0.941]

[0.723,0.822]

[0.581,0.691]

Sp

0.558

0.834

0.873

[0.538,0.578]

[0.818,0.849]

[0.860,0.887]

PPV

0.189

0.345

0.389

[0.168,0.211]

[0.307,0.384]

[0.347,0.433]

NPV

0.982

0.970

0.964

[0.974,0.989]

[0.962,0.977]

[0.955,0.972]

ACC

0.594

0.828

0.857

[0.575,0.613]

[0.813,0.841]

[0.843,0.870]

AUROC

0.733

0.804

0.792

[0.713,0.753]

[0.777,0.830]

[0.762,0.820]

Admission

n = 2287

Se

0.590

0.339

0.301

[0.564,0.616]

[0.314,0.365]

[0.276,0.327]

Sp

0.617

0.888

0.935

[0.590,0.643]

[0.871,0.906]

[0.921,0.948]

PPV

0.618

0.762

0.829

[0.590,0.644]

[0.727,0.795]

[0.794,0.862]

NPV

0.589

0.562

0.560

[0.562,0.615]

[0.540,0.583]

[0.539,0.581]

ACC

0.603

0.607

0.610

[0.585,0.622]

[0.588,0.626]

[0.591,0.629]

AUROC

0.603

0.614

0.618

[0.585,0.622]

[0.598,0.629]

[0.604,0.632]

48 h mortality

n = 44

Se

0.909

0.727

0.727

[0.795,1.000]

[0.545,0.886]

[0.545,0.886]

Sp

0.515

0.777

0.819

[0.496,0.534]

[0.760,0.793]

[0.804,0.834]

PPV

0.018

0.031

0.039

[0.011,0.026]

[0.019,0.046]

[0.023,0.057]

NPV

0.998

0.997

0.997

[0.996,1.000]

[0.994,0.999]

[0.994,0.999]

ACC

0.519

0.776

0.818

[0.499,0.538]

[0.760,0.792]

[0.804,0.833]

AUROC

0.712

0.752

0.773

[0.646,0.759]

[0.661,0.831]

[0.681,0.855]

30-day mortality

n = 209

Se

0.732

0.612

0.536

[0.651,0.809]

[0.526,0.699]

[0.445,0.627]

Sp

0.523

0.791

0.831

[0.503,0.543]

[0.774,0.807]

[0.816,0.846]

PPV

0.070

0.126

0.135

[0.056,0.084]

[0.099,0.152]

[0.106,0.166]

NPV

0.975

0.976

0.973

[0.967,0.983]

[0.970,0.983]

[0.966,0.980]

ACC

0.533

0.782

0.817

[0.513,0.553]

[0.766,0.798]

[0.802,0.832]

AUROC

0.627

0.702

0.684

[0.586,0.667]

[0.657,0.746]

[0.639,0.728]