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Table 2 Acute dysnatremias and mortality sorted by increasing serum-sodium

From: Acute Dysnatremias - a dangerous and overlooked clinical problem

Patient

Sex

Age

Serum-sodium (mmol/l) at hospital arrival

Duration of symptoms at arrival

Cause

Neurological signs/symptoms

Treatment given

Correction of s-sodium first 24 h

Time to death

1

Female

27

106

30 min.

Over hydration and gastroenteritis last 14 h.

Coma, seizures.

Hypertonic NaCl and furosemide.

21 mmol/l during 7 h.

Declared brain dead 16 h after arrival.

2

Male

18

121, falling to 115 before transfer to ICU.

6 h.

Water intoxication estimated to 20 L in 6 h.

Nausea, headache, confusion, decreased consciousness.

NaCl 9 mg/ml and mannitol.

30 mmol/l during 12 h.

Derived diabetes insipidus, sepsis and DIC, died within few days.

3

Female

20

123

1–2 h.

Over hydration before urinary sample, estimated to 10 L within 2–3 h.

Headache, dizziness, seizures, decreased consciousness.

NaCl 9 mg/ml and furosemide.

21 mmol/l during 18 h.

2 days.

4

Female

47

127

2 h and 45 min.

Exercise-associated hyponatremia.

Headache, vomiting, decreased consciousness (GCS 7).

NaCl 9 mg/ml and 3%, also mannitol and furosemide.

16 mmol/l during 4 h.

19 h after onset of symptoms.

5

Male

41

209

4 h.

Salt intoxication, drank mouthwash.

Status epilepticus, coma (GCS 3).

Glucose 50 mg/ml, NaCl 4,5 mg/ml and NaCl 9 mg/ml

18 mmol/l during 13 h, 27 mmol/l during 29 h.

72 h after intoxication.

6

Female

36

246

< 24 h.

Salt intoxication during excorcism.

Coma.

NaCl 9 mg/ml, glucose 50 mg/ml and furosemide.

53 mmol/l during 7 h.

Clinically brain dead 5 h after arrival.