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Table 4 Bleeding locations

From: Application of prothrombin complex concentrate for reversal of direct oral anticoagulants in clinical practice: indications, patient characteristics and clinical outcomes compared to reversal of vitamin K antagonists

 

Total (n = 346)

DOAC (n = 74)

Vitamin K antagonist (n = 272)

p

Intracranial

213

(61.6)

45

(60.8)

168

(61.8)

0.881

Upper/lower gastrointestinal

38

(11.0)

24

(18.9)

14

(8.8)

0.014

Superficial

22

(6.4)

4

(5.4)

18

(6.6)

0.705

Extremity

17

(4.9)

2

(2.7)

15

(5.5)

0.321

Abdominal

13

(3.8)

2

(2.7)

11

(4.0)

0.591

Thorax

11

(3.2)

4

(5.4)

7

(2.6)

0.218

Eye

6

(1.7)

1

(1.4)

5

(1.8)

0.776

Retroperitoneal

5

(1.4)

1

(1.4)

4

(1.5)

0.939

Haematuria

3

(0.9)

1

(1.4)

2

(0.7)

0.612

Epistaxis

2

(0.6)

0

(0.0)

2

(0.7)

0.459

Oral

1

(0.3)

0

(0.0)

1

(0.4)

0.601

  1. Abbreviation: DOAC direct oral anticoagulants