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Table 2 Anticoagulation characteristics

From: Application of prothrombin complex concentrate for reversal of direct oral anticoagulants in clinical practice: indications, patient characteristics and clinical outcomes compared to reversal of vitamin K antagonists

 

Total (n = 346)

DOAC (n = 74)

Vitamin K antagonist (n = 272)

p

Anticoagulation indication

 Not specified

27

(7.8)

10

(13.5)

17

(6.2)

 

 Atrial fibrillation

223

(64.5)

48

(64.9)

175

(64.3)

 

 Thromboembolic event

74

(21.4)

13

(17.6)

61

(22.4)

 

 Mechanical heart-valve

17

(4.9)

1

(1.4)

16

(5.9)

 

 Coagulopathy

5

(1.4)

2

(2.7)

3

(1.1)

0.090

Additional platelet aggregation inhibitor therapy

 None

285

(82.4)

62

(83.8)

223

(82.0)

 

 Acetylsalicylic acid

44

(12.7)

9

(12.2)

35

(12.9)

 

 Clopidogrel

13

(3.8)

1

(1.4)

12

(4.4)

 

 Acetylsalicylic acid + Clopidogrel

4

(1.2)

2

(2.7)

2

(0.7)

0.328

 Additional heparin

7

(2.0)

1

(1.4)

6

(2.2)

0.643

  1. Abbreviation: DOAC direct oral anticoagulants