Skip to main content
Fig. 2 | Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine

Fig. 2

From: Streptococcal M1 protein induces hyporesponsiveness and cytokine release from human arteries in a fibrinogen-dependent manner: a translational study

Fig. 2

Contraction induced by noradrenaline in human omental arteries incubated with plasma (10%) in the presence or absence of LPS (50 EU mL-1) or M1 protein (1 μg mL-1). The concentration-response curve to noradrenaline was shifted to the right after incubation with M1 protein reflected by an increase in noradrenaline concentration required to elicit half maximum response (P = 0.031). The area under the curve was significant smaller (P = 0.044) after incubation with M1 protein. The concentration-response curve after incubation with LPS did not statistically significantly differ from control. One way repeated measurement ANOVA. Values are means ± SE (n = 5)

Back to article page