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Table 3 Independent mortality predictors in all participants by Cox proportional hazards regression

From: Long-term mortality of acetaminophen poisoning: a nationwide population-based cohort study with 10-year follow-up in Taiwan

Variable

Crude Hazard Ratio (95% CI)

Adjusted Hazard Ratio (95% CI)a

APAP poisoning

 Yes

8.0 (6.3–10.2)

7.4 (5.8–9.6)

 No

1.0

1.0

Age (years)

 ≤ 20

1.0

1.0

 21–39

2.5 (1.3–4.7)

3.0 (1.5–5.6)

 40–64

7.8 (4.1–15.1)

6.2 (3.2–12.3)

 ≥ 65

41.4 (21.6–79.5)

14.9 (7.2–30.9)

Sex

 Male

2.6 (2.1–3.2)

2.1 (1.6–2.6)

 Female

1.0

1.0

DM

 Yes vs. No

8.3 (6.2–10.9)

1.6 (1.2–2.3)

CAD

 Yes vs. No

1.0 (7.7–12.9)

1.3 (0.9–1.8)

Stroke

 Yes vs. No

13.5 (1.0–18.3)

1.2 (0.8–1.7)

HTN

 Yes vs. No

9.1 (7.3–11.4)

1.5 (1.0–2.1)

Liver disease

 Yes vs. No

3.8 (3.0–4.8)

1.4 (1.1–1.9)

Renal disease

 Yes vs. No

3.5 (2.7–4.6)

1.1 (0.8–1.4)

Mental Disorder

 Yes vs. No

3.8 (3.0–4.7)

1.28 (0.9–1.5)

Cancer

 Yes vs. No

10.1 (7.3–14.0)

2.6 (1.8–3.6)

Geographic region

 Northern

0.2 (0.1–0.8)

0.1 (0.03–0.3)

 Central

0.2 (0.04–0.8)

0.1 (0.03–0.5)

 Southern

0.3 (0.1–1.1)

0.2 (0.04–0.5)

 Eastern

1.0

1.0

Monthly income

 NTD ≤ 15,840

4.5 (2.9–6.9)

2.2 (1.4–3.5)

 NTD 15840–25,000

2.3 (1.5–3.7)

1.6 (1.0–2.5)

 NTD ≥ 25,001

1.0

1.0

  1. aAdjusted for all the variables. APAP Acetaminophen, CI Confidence interval, DM Diabetes mellitus, CAD Coronary artery disease, HTN Hypertension, NTD New Taiwan dollar