Table 1 Patient characteristics
From: Therapeutic hypothermia in patients with coagulopathy following severe traumatic brain injury
Coagulopathy n = 32 | Non-coagulopathy n = 87 | P-value | |
|---|---|---|---|
Age (years) | 42 (22–56) | 42 (21–55) | 0.55 |
Male | 27 (87.1) | 52 (61.1) | < 0.01 |
Systolic blood pressure (mmHg) | 151 (124–170) | 142 (114–179) | 0.48 |
Heart rate (beats/min) | 83 (71–110) | 86 (70–106) | 0.89 |
Glasgow Coma Scale score | 6 (4–7) | 6 (4–7) | 0.60 |
Unreactive pupil or pupils | 14 (43.8) | 37 (42.5) | 1.00 |
Platelet counts (×104/mm3) | 23.7 (18.4–29.3) | 22.7 (17.1–27.4) | 0.52 |
APTT (s) | 42.9 (34.2–84.5) | 28.3 (25.5–34.3) | < 0.01 |
FDP (μg/mL) | 114.8 (92.5–168.3) | 30.9 (14.2–50.3) | < 0.01 |
Fibrinogen (mg/dL) | 206 (140–267) | 202 (165–243) | 0.87 |
TCDB classification | 0.77 | ||
Diffuse injury grade I | 0 (0) | 2 (2.3) | |
Diffuse injury grade II | 11 (34.4) | 25 (28.7) | |
Diffuse injury grade III | 7 (21.9) | 12 (13.8) | |
Diffuse injury grade IV | 1 (3.1) | 3 (3.5) | |
Non-evacuated mass/Evacuated mass | 1/12 | 4/41 | 0.68 |
Surgical operation for TBI | 16 (51.6) | 58 (66.7) | 0.19 |
Injury severity score | 25 (21–34) | 25 (17–30) | 0.09 |
AIS score for head | 4 (4–5) | 4 (4–5) | 0.16 |
Favorable outcome | 11 (34.4) | 44 (50.6) | 0.15 |
Survival rate | 18 (56.3) | 63 (72.4) | 0.12 |
Overall complication rate | 4 (12.5) | 12 (13.8) | 0.85 |