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Table 1 Patient characteristics

From: Therapeutic hypothermia in patients with coagulopathy following severe traumatic brain injury

  Coagulopathy n = 32 Non-coagulopathy n = 87 P-value
Age (years) 42 (22–56) 42 (21–55) 0.55
Male 27 (87.1) 52 (61.1) < 0.01
Systolic blood pressure (mmHg) 151 (124–170) 142 (114–179) 0.48
Heart rate (beats/min) 83 (71–110) 86 (70–106) 0.89
Glasgow Coma Scale score 6 (4–7) 6 (4–7) 0.60
Unreactive pupil or pupils 14 (43.8) 37 (42.5) 1.00
Platelet counts (×104/mm3) 23.7 (18.4–29.3) 22.7 (17.1–27.4) 0.52
APTT (s) 42.9 (34.2–84.5) 28.3 (25.5–34.3) < 0.01
FDP (μg/mL) 114.8 (92.5–168.3) 30.9 (14.2–50.3) < 0.01
Fibrinogen (mg/dL) 206 (140–267) 202 (165–243) 0.87
TCDB classification    0.77
 Diffuse injury grade I 0 (0) 2 (2.3)  
 Diffuse injury grade II 11 (34.4) 25 (28.7)  
 Diffuse injury grade III 7 (21.9) 12 (13.8)  
 Diffuse injury grade IV 1 (3.1) 3 (3.5)  
 Non-evacuated mass/Evacuated mass 1/12 4/41 0.68
Surgical operation for TBI 16 (51.6) 58 (66.7) 0.19
Injury severity score 25 (21–34) 25 (17–30) 0.09
 AIS score for head 4 (4–5) 4 (4–5) 0.16
Favorable outcome 11 (34.4) 44 (50.6) 0.15
Survival rate 18 (56.3) 63 (72.4) 0.12
Overall complication rate 4 (12.5) 12 (13.8) 0.85
  1. Values are presented as n (%) or median (interquartile ranges, IQRs)
  2. MTH mild therapeutic hypothermia, AIS abbreviated injury score, TBI traumatic brain injury, CT computed tomography, FDP fibrin degradation products, TCDB Traumatic Coma Data Bank