| With seizure (n = 83) | Without seizure (n = 312) | p-value |
---|---|---|---|
Head AIS (n, %) | |||
 2 | 18, 21.69 | 69, 22.11 | 0.93 |
 3 | 25, 30.12 | 106, 33.97 | 0.51 |
 4 | 26, 31.23 | 90, 28.85 | 0.66 |
 5 | 14, 16.87 | 47, 15.06 | 0.69 |
GCS (n, %) | |||
 7-8 | 41, 49.40 | 149, 47.76 | 0.79 |
 5-6 | 33, 39.76 | 123, 39.42 | 0.96 |
 3-4 | 9, 10.84 | 40, 12.82 | 0.63 |
VPA concentrations (ug/ml): mean ± sd, median | |||
 Day1 | 59.12 ± 24.18, 59.0 | 63.96 ± 16.60, 62.5 | 0.03 |
 Day2 | 61.53 ± 18.23, 62.0 | 65.92 ± 15.37, 62.0 | 0.03 |
 Day3 | 63.63 ± 19.03, 63.0 | 69.05 ± 26.30, 71.5 | 0.08 |
 Day4 | 65.56 ± 16.26, 66.0 | 68.24 ± 24.18, 70.0 | 0.35 |
 Day5 | 68.14 ± 24.18, 69.0 | 70.05 + 23.26, 68.0 | 0.53 |
 Day6 | 73.22 ± 29.13, 70.0 | 75.02 ± 27.04, 73.5 | 0.61 |
 Day7 | 69.92 ± 26.04, 72.0 | 71.35 + 21.57, 72.5 | 0.62 |
Weight (kg): mean ± sd, median | 73.27 ± 12.71, 72.0 | 72.12 ± 10.95, 70.5 | 0.41 |
ICULOS (days): mean ± sd, median | 19.25 ± 6.52, 18.0 | 15.31 ± 7.10, 16.0 | <0.01 |
HLOS (days): mean ± sd, median | 20.32 ± 7.35, 21.0 | 19.01 ± 7.78, 19.0 | 0.17 |
Mortality at discharge (n, %) | 11,13.25 | 43, 13.78 | 0.90 |
Mortality at 3 months after injury (n, %) | 13, 15.66 | 47, 15.06 | 0.97 |
GOS at 3 months after injury | |||
 1-3 (n, %) | 72, 86.74 | 256, 82.05 | 0.31 |
 4-5 (n, %) | 11, 13.25 | 56, 17.94 | 0.31 |