Dysfunction | Grade 0 | Grade 1 | Grade 2 | Grade 3 | Grade 4 |
---|---|---|---|---|---|
Denver Score | |||||
Pulmonary, PaO2/FIO2, [mmHg] | >208 | 208–165 | 165–83 | <83 | |
Hepatic, bilirubin, [μmol/L] | <34 | 34–68 | 69–137 | >137 | |
Renal creatinine, [μmol/L] | <159 | 160–210 | 211–420 | >420 | |
Cardiac inotropesa | No inotropes | Only 1 inotrope at a small dose | Any inotrope at moderate dose or >1 agent at small dose | Any inotrope at large dose or >2 agents at moderate dose | |
SOFA score | |||||
Pulmonary, PaO2/FIO2, [mmHg] | >400 | ≤400 | ≤300 | ≤200 | ≤100 |
Coagulation, platelet count, [×103/μL] | >150 | ≤150 | ≤100 | ≤50 | ≤20 |
Hepatic, bilirubin, [μmol/L] | ≤20 | 20–32 | 33–101 | 102–204 | >204 |
Cardiovascular, inotropesb in μg/kg/min | No hypotension | Mean arterial pressure <70 mmHg | Dopa ≤5 or any Dobu dose | Dopa >5 or Epi ≤0.1 or Nor ≤ 0.1 | Dopa >15 or Epi >0.1 or Nor >0.1 |
Renal, creatinine, [μmol/L] | <110 | 110–170 | 171–299 | 300–440 | >440 |
Central nervous system, GCS | 15 | 13–14 | 10–12 | 6–9 | <6 |
MODS | |||||
Pulmonary, PaO2/FIO2, [mmHg] | >300 | 226–300 | 151–225 | 76–150 | ≤51 |
Renal, creatinine, [μmol/L] | ≤100 | 101–200 | 201–350 | 351–500 | >500 |
Hepatic, bilirubin, [μmol/L] | ≤20 | 21–60 | 61–120 | 121–240 | >240 |
Cardiovascular, PARc | ≤10.0 | 10.1–15.0 | 15.1–20.0 | 20.1–30.0 | >30.0 |
Coagulation, platelet count, ×103/μL | >120 | 81–120 | 51–80 | 21–50 | ≤20 |
Central nervous system, GCS | 15 | 13–14 | 10–12 | 6–9 | <6 |