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Table 6 Univariate and multivariate analyses evaluating the association of absolute value of Chloride (mmol/L) on 30-day mortality

From: Hyperchloremia is associated with 30-day mortality in major trauma patients: a retrospective observational study

Variables Univariate analysis Multivariate analysis
OR (95 % CI) p value OR (95 % CI) p value
Age (per year) 1.014 (0.994–1.034) 0.17 .  
ISS 1.080 (1.033–1.130) 0.001 .  
RTS 0.621 (0.511–0.754) <0.001 0.720 (0.552–0.939) 0.02
Mechanical ventilation (yes) 21.838 (2.929–162.842) 0.003 .  
Transfusion (yes) 6.750 (2.290–19.894) 0.001 3.296 (0.756–14.372) 0.11
Hypotension (SBP < 90, yes) 4.477 (1.971–10.168) <0.001 .  
Hypothermia (BT < 35 °C, yes) 3.828 (1.626–9.012) 0.002 .  
Cumulative fluid balance at 48 h (per 1L) 1.000 (1.000–1.000)a 0.01 .  
Base deficit at 48 h (per 1mmol/L) 0.740 (0.631–0.868) <0.001 0.748 (0.619–0.905) 0.003
Chloride at 48 h (per 1mmol/L) 1.151 (1.084–1.222) <0.001 1.075 (1.006–1.150) 0.03
Use of vasopressor (yes) 29.186 (6.789–125.472) <0.001 9.758 (2.044–46.600) 0.004
Use of loop diuretics (yes) 3.243 (1.432–7.344) 0.005 .  
AKI (yes) 7.130 (3.112–16.336) <0.001 . .
  1. OR odds ratio, CI confidence interval, ISS injury severity score, RTS revised trauma score, AKI acute kidney injury, SBP systolic blood pressure, BT body temperature, AKI acute kidney injury
  2. a(1.000027–1.000216)
  3. p value for the Hosmer-Lemeshow goodness-of-fit-test was 0.148