Fig. 2
Time course of prothrombin time index (a) activated partial thromboplastin time (b) antithrombin III (c) and platelet count (d) during the first 7 days after trauma categorized according to the dose of fibrinogen concentrate administered. Control (white), 1–4 g FC (yellow), 5–9 g FC (orange), ≥10 g FC (red). Data shown are median, interquartile range and range. Shaded areas represent normal laboratory value ranges (PTI: 70–120 %; aPTT: 26–35 s; AT-III: 75–125 %; Plt 150–350 × 109/l) and dots represent outliers. ER, values on admission to the emergency room; not indicated = not significant; *P < 0.05; **P < 0.01; ***P < 0.001; in the Newman-Keuls multiple comparisons between all four groups