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Table 4 Genotypic and allelic frequency distribution in patients with sepsis and non-sepsis

From: Clinical relevance of single nucleotide polymorphisms within the 13 cytokine genes in North Indian trauma hemorrhagic shock patients

Cytokine gene polymorphism Genotype Non-sepsis Sepsis p value OR (95 % CI)
   f (%) f(%)   
   n = 89 n = 25   
IL-1α(−889) CC 45(50.56) 21(84)   1
TC 32(35.96) 3(12) 0.01 0.20(0.05–0.73)
TT 12(13.48) 1(4)   0.17(0.02–1.4)
C 122(68.5) 45(90)   1
T 56(31.5) 5(10) 0.002 0.24(0.07-0.6)
TNF-α(−308) AA 3(3.3) 2(8)   1
GA 17(19.1) 1(4) 0.09 0.08(0.05–1.3)
GG 69(77.6) 22(88)   0.47(0.07–3.0)
A 23(13) 5(10)   1
G 155(87) 45(90) 0.57 1.3(0.46–4.7)
TNF-α(−238) GG 78(87.7) 19(76)   1
GA 10(11.2) 4(16) 0.13 0.2 (0.13–2.8)
AA 1(1.1) 2(8)   0.12(0.01–1.4)
G 166(93.2) 42(84) 0.04 1
A 12(6.8) 8(16)   2.6(0.87–7.5)
IL-4(−1098) TT 66(74.1) 12(48)   1
TG 21(23.6) 9(36) 0.006 2.3(0.87–6.3)
GG 2(2.3) 4(16)   11(1.8–66.9)
T 153(86) 33(82) 0.001 1
G 25(14) 17(18)   3.1(1.4–6.8)
IL-10(−1082) GG 5(5.7) 4(16)   1
GA 33(37) 2(8) 0.01 0.07 (0.01–0.52)
AA 51(57.3) 19(76)   0.46 (0.11–1.9)
G 30(16.9) 10(20) 0.60 1
A 148(83.1) 40(80)   0.8(0.34–2.0)
IL-10(−819) CC 63(70.7) 16(64)   1
CT 22(24.7) 6(24) 0.39 0.10 (0.03–3.0)
TT 4(4.6) 3(12)   0.65 (0.14–2.9)
C 148(83.1) 12(76) 0.001 1
T 30(16.9) 31(24)   12.7(5.5–30.1)