Effect of regulating airway pressure on intrathoracic pressure and vital organ perfusion pressure during cardiopulmonary resuscitation: a non-randomized interventional cross-over study

Table 1 Summary of hemodynamic data

	STD	ACD	ACD-ITD	ACD-ITPR
SBP	59.4 ± 7.7	63.1 ± 7.9^*	71.3 ± 9.8^,*	75.4 ± 11.6^,*
DBP	21.7 ± 3.6	16.4 ± 3.0	21.5 ± 4.6	23.8 ± 5.4^**
Pra max	58.2 ± 7.6	68.1 ± 10.5^*	70.4 ± 9.6^*	74.3 ± 9.8^*
Pra min	1.8 ± 1.6	−0.5 ± 1.7	−1.4 ± 1.6*	−2.4 ± 1.4^*
Pra mean	23.3 ± 2.9	21.8 ± 3.8	22.5 ± 3.3	23.7 ± 3.6
ICP	20.9 ± 1.1	19.0 ± 1.5	19.7 ± 1.7	19.9 ± 2.1
CePP	13.0 ± 3.1	13.2 ± 3.0	17.1 ± 4.1	19.0 ± 5.3^,*
CPP	12.9 ± 3.0	11.6 ± 1.7	16.7 ± 2.9^**	18.1 ± 3.6^,*
CBF	37.7 ± 6.4	48.8 ± 8.7^*	53.3 ± 9.0^*	57.4 ± 10.5^*
ETCO₂	21.5 ± 2.2	23.7 ± 3.1	30.3 ± 1.9^,*	30.3 ± 3.5^,*

Values are shown as mean ± SEM. All pressures are in mm Hg and all flows in mL/min. Data are derived from 8 animals except for ICP, CePP and ETCO₂ (n = 6)
STD standard, ACD active compression decompression, ITD impedance threshold device, ITPR intrathoracic pressure regulator, SBP and DBP systolic and diastolic aortic blood pressure, Pra right atrial pressure, ICP intracranial pressure, CePP cerebral perfusion pressure, CPP coronary perfusion pressure, CBF carotid blood flow, ETCO ₂ end-tidal CO₂; max, maximum,;min, minimum
*denotes p < 0.05 for STD vs. (ACD, ACD ITD, ACD ITPR)
**denotes p < 0.05 for ACD vs. (ACD ITD, ACD ITPR)

ISSN: 1757-7241