| |
Baseline
|
Resuscitation
|
3 h
|
6 h
|
|---|
|
Arterial O
2
(mmHg)
|
|
Control
|
475 ± 18
|
460 ± 15
|
497 ± 16
|
470 ± 15
|
|
LR
|
493 ± 15
|
513 ± 10
|
515 ± 15
|
499 ± 11
|
|
NS
|
478 ± 25
|
474 ± 21
|
490 ± 17
|
470 ± 16
|
|
Arterial CO
2
(mmHg)
|
|
Control
|
47 ± 4
|
48 ± 4
|
45 ± 3
|
45 ± 4
|
|
LR
|
44 ± 3
|
43 ± 3
|
45 ± 3
|
43 ± 2
|
|
NS
|
47 ± 2
|
43 ± 2
|
44 ± 2
|
44 ± 1
|
|
Venous O2 (mmHg)
|
|
Control
|
55 ± 5
|
60 ± 4
|
58 ± 5
|
50 ± 5
|
|
LR
|
56 ± 2
|
53 ± 3
|
36 ± 1*♣
|
36 ± 1*♣
|
|
NS
|
54 ± 2
|
53 ± 2
|
46 ± 2*♣
|
43 ± 1*♣§
|
|
Venous CO2 (mmHg)
|
|
Control
|
60 ± 5
|
57 ± 4
|
50 ± 3
|
51 ± 5
|
|
LR
|
53 ± 2
|
50 ± 2
|
56 ± 2
|
56 ± 1
|
|
NS
|
59 ± 5
|
50 ± 2
|
55 ± 1
|
55 ± 1
|
|
Arterial oxygen content (ml O2/dL blood)
|
|
Control
|
13.8 ± 0.6
|
13.8 ± 0.5
|
13.6 ± 0.3
|
13.3 ± 0.7
|
|
LR
|
14.7 ± 0.3
|
7.6 ± 0.3*♣
|
8.5 ± 0.6*♣
|
7.8 ± 0.4*♣
|
|
NS
|
13.2 ± 0.9
|
6.4 ± 0.4*♣
|
7.9 ± 0.4*♣
|
7.3 ± 0.4*♣
|
|
Venous oxygen content (ml O2/dL blood)
|
|
Control
|
9.9 ± 0.5
|
9.9 ± 0.7
|
9.3 ± 0.6
|
7.7 ± 0.9
|
|
LR
|
10.8 ± 0.2
|
4.3 ± 0.2*♣
|
3.5 ± 0.2*♣
|
3.1 ± 0.2*♣
|
|
NS
|
8.6 ± 0.6
|
4.1 ± 0.3*♣
|
4.2 ± 0.3*♣
|
3.8 ± 0.3*♣
|
|
Oxygen extraction (%)
|
|
Control
|
28 ± 4
|
29 ± 3
|
32 ± 3
|
32 ± 3
|
|
LR
|
28 ± 2
|
43 ± 2*
|
57 ± 3*
|
60 ± 3*
|
|
NS
|
35 ± 5
|
36 ± 3
|
47 ± 3*
|
49 ± 3*
|
- Animal groups include control (C, n = 6), hemorrhage with LR resuscitation (LR, n = 6), and hemorrhage with normal saline resuscitation (NS, n = 6). Data are expressed as means ± SE.
- *p < 0.05 compared to corresponding baseline values within the group; §p < 0.05 LR vs NS groups; and ♣p < 0.05 compared to corresponding control values.
