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Table 3 Stepwise multivariate logistic regression analysis: Predictors of in-hospital mortality

From: A retrospective analysis of geriatric trauma patients: venous lactate is a better predictor of mortality than traditional vital signs

Variable Odds ratio 95% CI P value
Model 1: Lactate (r2=0.29; H-L=0.87)
VL ≥ 2.5 mM 2.62 1.49 – 4.58 < 0.001
Glasgow coma scale 3-12 11.49 6.20 – 21.30 < 0.001
Injury severity score ≥ 16 3.40 1.86 – 6.21 < 0.001
Age ≥ 85 years 2.10 1.17 – 3.77 0.01
Model 2: Occult hypoperfusion* (r2=0.28; H-L=0.55)
Occult hypoperfusion* 2.12 1.20 – 3.77 0.01
Glasgow coma scale 3-12 12.28 6.63 – 22.74 < 0.001
Injury severity score ≥ 16 3.47 1.90 – 6.36 < 0.001
Age ≥ 85 years 2.02 1.13 – 3.61 0.02
Model 2: TVS (r2=0.28; H-L=0.77)
Abnormal TVS† 1.71 0.74 – 3.93 0.21
Glasgow coma scale 3-12 14.97 8.52 – 26.29 < 0.001
Injury severity score ≥ 16 3.88 2.23 - 6.76 < 0.001
Age ≥ 85 years 1.92 1.11 – 3.32 0.02
Model 3: Shock index (r2=0.27; H-L=0.69)
Shock index ≥ 1 1.18 0.39 – 3.58 0.78
Glasgow coma scale 3-12 15.38 8.69 – 27.23 < 0.001
Injury severity score ≥ 16 3.86 2.19 – 6.81 < 0.001
Age ≥ 85 years 1.85 1.07 – 3.22 0.03
Model 4: Lactate and TVS (r2=0.29; H-L=0.72)
VL ≥ 2.5 mM 2.58 1.47 – 4.52 < 0.001
Abnormal TVS† 1.46 0.62 - 3.47 0.39
Glasgow coma scale 3-12 11.23 6.06 – 20.83 < 0.001
Injury severity score ≥ 16 3.36 1.84 - 6.13 < 0.001
Age ≥ 85 years 2.14 1.19 – 3.84 0.01
  1. Stepwise logistic regression, with entry and exit values set at p < 0.15 for all models.
  2. Abbreviations: CI, confidence interval; VL, venous lactate; TVS, traditional vital signs; H-L, hosmer-lemeshow goodness of fit statistic.
  3. *Occult hypoperfusion: VL ≥ 2.5 mM with normal TVS.
  4. †Abnormal TVS: Systolic blood pressure < 90 mm Hg and/or heart rate > 120 beats/min.