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Table 1 Demographic and clinical characteristics of patients treated with and without mild therapeutic hypothermia

From: ACS network-based implementation of therapeutic hypothermia for the treatment of comatose out-of-hospital cardiac arrest survivors improves clinical outcomes: the first European experience

Variable

Patients undergoing MTH procedure

Control group

p

 

(n = 32)

(n = 33)

 

Demographic characteristics

Age [years]

65.6 ± 19.0

62.7 ± 9.8

ns

Gender: men/women

25 (78.1%)/7 (21.9%)

26 (78.8%)/7 (21.2%)

ns

Medical history

Concomitant diabetes

13 (40.6%)

13 (39.4%)

ns

Prior stroke

4 (12.5%)

3 (9.1%)

ns

Prior myocardial infarction

8 (25.0%)

13 (39.4%)

ns

Details regarding OHCA

First-recorded cardiac rhythm

  

ns

  Ventricular fibrillation or pulseless ventricular tachycardia

26 (81.3%)

26 (78.8%)

  Asystole

5 (15.6%)

6 (18.2%)

  Pulseless electrical activity

1 (3.1%)

1 (3.0%)

Initiation of cardiopulmonary resuscitation by bystanders

12 (37.5%)

10 (30.3%)

ns

Time between OHCA and ROSC [minutes]

30.0 (25.0-56.0)

23.0 (18.0-37.0)

ns

Duration of cardiopulmonary resuscitation [minutes]

25.0 (15.0-51.0)

20.0 (11.0-45.0)

ns

Patient status on admission and in-hospital management

Glasgow Coma Score on hospital admission

  

ns

  3-4 points

22 (68.8%)

18 (54.6%)

  5-6 points

7 (21.9%)

11 (33.3%)

  7-8 points

3 (9.3%)

4 (12.1%)

Arterial pH on hospital admission

7.26 (7.20-7.33)

7.30 (7.16-7.36)

ns

Shock on hospital admission

15 (46.9%)

14 (42.4%)

ns

LVEF on hospital admission [%]

35.0 (30.0-45.0)

30.0 (25.0-40.0)

ns

Underlying cause of OHCA

  

p < 0.04

  STEMI

24 (75.0%)

22 (66.7%)

  NST-ACS

2 (6.2%)

9 (27.3%)

  Other

6 (18.8%)

2 (6.0%)

Presence of coronary artery disease

  

ns

  single-vessel

7 (21.9%)

11 (33.3%)

  multi-vessel

17 (53.1%)

20 (60.6%)

  lack of significant coronary lesions

8 (25.0%)

2 (6.1%)

Treatment with PCI

24 (75.0%)

27 (81.8%)

ns

Use of intra-aortic balloon counterpulsation

4 (12.5%)

9 (27.3%)

ns

  1. LVEF Left ventricular ejection fraction; MTH Mild therapeutic hypothermia; NST-ACS Non-ST-segment elevation acute coronary syndrome; OHCA Out-of-hospital cardiac arrest; PCI Percutaneous coronary intervention; ROSC Successful return of spontaneous circulation; STEMI ST-segment elevation myocardial infarction.