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Table 1 Demographic and clinical characteristics of patients treated with and without mild therapeutic hypothermia

From: ACS network-based implementation of therapeutic hypothermia for the treatment of comatose out-of-hospital cardiac arrest survivors improves clinical outcomes: the first European experience

Variable Patients undergoing MTH procedure Control group p
  (n = 32) (n = 33)  
Demographic characteristics
Age [years] 65.6 ± 19.0 62.7 ± 9.8 ns
Gender: men/women 25 (78.1%)/7 (21.9%) 26 (78.8%)/7 (21.2%) ns
Medical history
Concomitant diabetes 13 (40.6%) 13 (39.4%) ns
Prior stroke 4 (12.5%) 3 (9.1%) ns
Prior myocardial infarction 8 (25.0%) 13 (39.4%) ns
Details regarding OHCA
First-recorded cardiac rhythm    ns
  Ventricular fibrillation or pulseless ventricular tachycardia 26 (81.3%) 26 (78.8%)
  Asystole 5 (15.6%) 6 (18.2%)
  Pulseless electrical activity 1 (3.1%) 1 (3.0%)
Initiation of cardiopulmonary resuscitation by bystanders 12 (37.5%) 10 (30.3%) ns
Time between OHCA and ROSC [minutes] 30.0 (25.0-56.0) 23.0 (18.0-37.0) ns
Duration of cardiopulmonary resuscitation [minutes] 25.0 (15.0-51.0) 20.0 (11.0-45.0) ns
Patient status on admission and in-hospital management
Glasgow Coma Score on hospital admission    ns
  3-4 points 22 (68.8%) 18 (54.6%)
  5-6 points 7 (21.9%) 11 (33.3%)
  7-8 points 3 (9.3%) 4 (12.1%)
Arterial pH on hospital admission 7.26 (7.20-7.33) 7.30 (7.16-7.36) ns
Shock on hospital admission 15 (46.9%) 14 (42.4%) ns
LVEF on hospital admission [%] 35.0 (30.0-45.0) 30.0 (25.0-40.0) ns
Underlying cause of OHCA    p < 0.04
  STEMI 24 (75.0%) 22 (66.7%)
  NST-ACS 2 (6.2%) 9 (27.3%)
  Other 6 (18.8%) 2 (6.0%)
Presence of coronary artery disease    ns
  single-vessel 7 (21.9%) 11 (33.3%)
  multi-vessel 17 (53.1%) 20 (60.6%)
  lack of significant coronary lesions 8 (25.0%) 2 (6.1%)
Treatment with PCI 24 (75.0%) 27 (81.8%) ns
Use of intra-aortic balloon counterpulsation 4 (12.5%) 9 (27.3%) ns
  1. LVEF Left ventricular ejection fraction; MTH Mild therapeutic hypothermia; NST-ACS Non-ST-segment elevation acute coronary syndrome; OHCA Out-of-hospital cardiac arrest; PCI Percutaneous coronary intervention; ROSC Successful return of spontaneous circulation; STEMI ST-segment elevation myocardial infarction.