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Table 5 Complications and toxic agents in 1065 cases of acute poisoning in Oslo during one year 2008–2009

From: A one-year observational study of all hospitalized acute poisonings in Oslo: complications, treatment and sequelae

  Opioids TCA Cardiovascular drugs Amphet-amine Cocaine GHB Neuro-leptics Other anti-depressants BZD Ethanol BZD-like substances CO/fire smoke Paracet-amol1 Others Total % of total
n poisonings 114 13 18 25 13 85 60 46 160 194 58 48 116 115 1065  
n with complications 64 7 9 12 6 35 17 13 41 48 14 8 16 32 322  
% with complications 562 54 50 48 46 41 28 28 26 25 24 17 14 28 30  
Mean n of complications per admission 1.1 1.3 0.9 0.8 0.8 0.6 0.5 0.4 0.4 0.3 0.4 0.2 0.2 0.4 0.5  
% observed in ICU 58 85 17 36 54 59 66 54 48 44 56 35 41 43 49  
Respiratory depression 41 3 2 4 4 16 3 2 20 13 9 5 2 5 129 12
Prolonged QTc 9 3   1   7 8 5 8 10 2   2 9 64 6
Hypotension 9 1 2 2   4 3   5 12 4   3 5 50 5
Pneumonia 12 1 1 1 1 2 3 2 4 5 4 2 1 4 43 4
Convulsions 7 2 1 3 1 3 5 5 1 4    1 3 36 3
Arrhythmia 6 2 6 1   9    1 2   1 3 4 35 3
Hypothermia 6 1   2   6 1   5 10    2 1 34 3
Rhabdomyolysis 8     1   1 1 3 2    1 1 18 2
Acute renal failure 6 1 2 2 1     1 1    2 1 17 2
Cardiac arrest ROSC 6     1     2      13 104 1
Allergic reaction 1      1    1 2    65   11 1
Prolonged QRS 1 3      1   2      2 9 1
Cerebral damage 3     1 1       1 1 16 87 1
Hypoglycemia 2         3      2 7 1
Others 7   2 3   1 4 2 4   3 2 4 5 37 3
  1. BZD benzodiazepines, GHB gamma-hydroxybutyric acid, ICU intensive care unit, ROSC return of spontaneous circulation, TCA tricyclic antidepressants.
  2. 1 Including a paracetamol–codeine combination drug.
  3. 2 77% among methadone.
  4. 3 After inhalation of propane and Freon gas in a car.
  5. 4 Of which four died and three developed permanent cerebral sequelae.
  6. 5 Allergic reaction to intravenous N-acetylcysteine administration.
  7. 6 Suicide attempt with insulin.
  8. 7 Of which two patients died and three developed permanent sequelae.