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Table 2 Unadjusted and adjusted Cox regression hazard ratios of mortality and acute readmission, respectively, within 30 and 7 days for patients discharged with nonspecific diagnoses compared to disease-specific diagnoses, stratified into short and lengthier hospital courses

From: Acute patients discharged without an established diagnosis: risk of mortality and readmission of nonspecific diagnoses compared to disease-specific diagnoses

 

Mortality

Readmission

30-day outcomes

Nonspecific discharge diagnosis

Disease-specific discharge diagnosis

Nonspecific discharge diagnosis

Disease-specific discharge diagnosis

Short hospital courses

(3 - <12 h)

Number of events (%)

304 (45.0%)

372 (55.0%)

3460 (47.3%)

3856 (52.7%)

HR

Unadjusted

0.79 (0.68–0.92)

(ref)

0.87 (0.83–0.91)

(ref)

Adjusted*

0.97 (0.83–1.13)

(ref)

0.94 (0.90–0.98)

(ref)

Lengthier hospital courses

(12–168 h)

Number of events (%)

409 (17.8%)

1885 (82.2%)

2859 (22.2%)

10,036 (77.8%)

HR

Unadjusted

0.62 (0.55–0.68)

(ref)

0.80 (0.77–0.83)

(ref)

Adjusted*

0.94 (0.85–1.05)

(ref)

0.95 (0.91–0.99)

(ref)

7-day outcomes

    

Short hospital courses

(3 - <12 h)

HR

Unadjusted

0.70 (0.52–0.93)

(ref)

0.85 (0.80–0.91)

(ref)

Adjusted*

0.84 (0.63–1.12)**

(ref)

0.92 (0.86–0.98)

(ref)

Lengthier hospital courses

(12–168 h)

HR

Unadjusted

0.48 (0.39–0.59)

(ref)

0.88 (0.83–0.93)

(ref)

Adjusted*

0.72 (0.57–0.88)

(ref)

0.97 (0.91–1.03)

(ref)

  1. Abbreviations HR = hazard ratio, CI = confidence interval
  2. † Death before readmission was considered a competing event
  3. * Adjusted for demographics (age and sex), socioeconomics (educational level, employment, civil status, cohabitation status, income, immigration status and country of origin), comorbidity (M3 comorbidity score and M3 cancer diagnosis), administrative information (time and day of arrival, time and day of discharge, length of stay) and laboratory information (whether at least 5 blood tests were analyzed among the 16 most frequent analyses and number of abnormal results among these)
  4. ** Not adjusted for all socioeconomic variables and no administrative variables due to limited number of events