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Table 1 Demographic and resuscitation parameters in polytrauma patients who had urgent surgery and were admitted to ICU

From: Outcome of severely injured patients in a unique trauma system with 24/7 double trauma surgeon on-call service

 

Total population

(n = 313)

Mortality

(n = 59)

Survival

(n = 254)

P-value

Age (years)

44 (27–59)

56 (40–73)

39 (25–56)

< 0.001*

Male gender

221 (71)

42 (71)

179 (71)

1.0

Blunt MOI

285 (91)

56 (95)

229 (90)

0.32

ISS

33 (24–38)

38 (29–48)

29 (22–38)

< 0.001*

AIS head

3 (0–4)

4 (2–5)

3 (0–4)

0.004*

AIS face

0 (0–1)

0 (0–2)

0 (0–1)

0.34

AIS chest

3 (2–4)

3 (3–4)

3 (2–4)

0.002*

AIS abdomen

2 (0–3)

2 (0–4)

2 (0–2)

0.09

AIS pelvis/extremities

3 (1–3)

3 (2–3)

3 (0–3)

0.29

AIS external

0 (0–1)

0 (0–1)

0 (0–1)

0.55

SBP_ED (mmHg)

114 (90–133)

111 (74–140)

115 (91–132)

0.29

SBP ≤ 90 mmHg_ED

84 (27)

22 (37)

62 (24)

0.03*

Hb_ED (mEq/L)

7.9 (7.0–8.9)

7.6 (6.1–8.4)

8.0 (7.2–8.9)

0.004*

pH_ED

7.31 (7.24–7.37)

7.25 (7.10–7.34)

7.32 (7.26–7.37)

 < 0.001*

PaC02_ED (mmHg)

45 (40–52)

48 (43–57)

44 (39–51)

0.003*

BD _ED (mEql/L)

−4.0 (−7.0–1.0)

−7.0 (−10.1–3.0)

−3.0 (−6.0–1.0)

< 0.001*

PT_ED (sec)

14.7 (13.3–17.4)

15.6 (14.3–21.1)

14.3 (13.1–16.8)

< 0.001*

Temperature_ED (oC)

35.4 (34.5–36.4)

35.1 (34.1–35.9)

35.5 (34.5–36.5)

0.17

SBP_ICU (mmHg)

117 (101–135)

115 (95–135)

118 (104–135)

0.15

Hb_ICU (mmol/L)

7.4 (6.6–8.1)

7.3 (6.2–7.8)

7.4 (6.7–8.2)

0.09

pH_ICU

7.34 (7.28–7.38)

7.30 (7.23–7.34)

7.34 (7.29–7.38)

< 0.001*

PaCO2_ICU (mmHg)

41 (36–46)

43 (38–50)

41 (36–46)

0.048*

BD_ICU (mEq/L)

−4.1 (−6.6–2.1)

−5.5 (−10.0–3.4)

−4.0 (−5.9–1.9)

< 0.001*

Temperature_ICU (oC)

35.1 (34.4–35.9)

35.1 (34.1–35.7)

35.2 (34.4–36.0)

0.15

UO_ICU (ml)

145 (80–300)

165 (80–363)

140 (80–300)

0.32

Resuscitation parameters

Crystalloids ≤ 8h (L)

5.3 (3.9–7.2)

6.2 (3.9–6.7)

5.2 (3.9–6.7)

0.003*

PRBC ≤ 8h (U)

3 (0–7)

5 (2–13)

3 (0–6)

0.003*

FFP ≤ 8h (U)

3 (0–6)

4 (1–10)

2 (0–6)

0.003*

PLT ≤ 8h (U)#

0 (0–1)

1 (0–2)

0 (0–1)

0.002*

Crystalloids ≤ 24h (L)

8.6 (6.7–11.2)

11.3 (8.0–13.6)

8.3 (6.6–10.6)

 < 0.001*

PRBC ≤ 24h (U)

4 (0–8)

5 (1–13)

3 (0–7)

0.046*

PRBC ≥ 10 units ≤ 24h

57 (18)

19 (32)

38 (15)

0.002*

FFP ≤ 24h (U)

4 (0–8)

5 (0–14)

3 (0–8)

0.03*

PLT ≤ 24h (U)#

0 (0–2)

1 (0–3)

0 (0–1)

0.03*

TXA ≤ 24h

244 (78)

46 (78)

198 (78)

1.0

Outcome parameters

Ventilator days

6 (2–11)

6 (2–13)

6 (2–11)

0.69

ICU LOS (days)

7 (3–13)

6 (2–13)

7 (3–14)

0.24

H-LOS (days)

22 (12–34)

7 (2–13)

25 (17–36)

 < 0.001*

MODS

51 (16)

18 (31)

33 (13)

0.003*

ARDS

12 (4)

2 (3)

10 (4)

1.0

Infectious complications

140 (45)

17 (29)

123 (48)

0.006*

Thrombo-embolic complications

34 (11)

4 (7)

30 (12)

0.36

  1. Data are expressed in median (IQR) or absolute numbers (%)
  2. MOI mechanism of injury, ISS injury severity score, AIS abbreviated injury scale, ED emergency department, SBP systolic blood pressure, Hb hemoglobin, PaC02 partial pressure of carbon dioxide in arterial blood, BD base deficit, PT prothrombin time, UO urinary output first hr in ICU, PRBC packed red blood cells, FFP fresh frozen plasma, PLT platelets, TXA tranexamic acid, ICU intensive care unit, LOS length of stay, H-LOS hospital length of stay, MODS multiple organ dysfunction syndrome, ARDS adult respiratory distress syndrome
  3. *Statistically significant
  4. #1 unit of platelets contains 5 donors