Total population (n = 313) | Mortality (n = 59) | Survival (n = 254) | P-value | |
---|---|---|---|---|
Age (years) | 44 (27–59) | 56 (40–73) | 39 (25–56) | < 0.001* |
Male gender | 221 (71) | 42 (71) | 179 (71) | 1.0 |
Blunt MOI | 285 (91) | 56 (95) | 229 (90) | 0.32 |
ISS | 33 (24–38) | 38 (29–48) | 29 (22–38) | < 0.001* |
AIS head | 3 (0–4) | 4 (2–5) | 3 (0–4) | 0.004* |
AIS face | 0 (0–1) | 0 (0–2) | 0 (0–1) | 0.34 |
AIS chest | 3 (2–4) | 3 (3–4) | 3 (2–4) | 0.002* |
AIS abdomen | 2 (0–3) | 2 (0–4) | 2 (0–2) | 0.09 |
AIS pelvis/extremities | 3 (1–3) | 3 (2–3) | 3 (0–3) | 0.29 |
AIS external | 0 (0–1) | 0 (0–1) | 0 (0–1) | 0.55 |
SBP_ED (mmHg) | 114 (90–133) | 111 (74–140) | 115 (91–132) | 0.29 |
SBP ≤ 90 mmHg_ED | 84 (27) | 22 (37) | 62 (24) | 0.03* |
Hb_ED (mEq/L) | 7.9 (7.0–8.9) | 7.6 (6.1–8.4) | 8.0 (7.2–8.9) | 0.004* |
pH_ED | 7.31 (7.24–7.37) | 7.25 (7.10–7.34) | 7.32 (7.26–7.37) | < 0.001* |
PaC02_ED (mmHg) | 45 (40–52) | 48 (43–57) | 44 (39–51) | 0.003* |
BD _ED (mEql/L) | −4.0 (−7.0–1.0) | −7.0 (−10.1–3.0) | −3.0 (−6.0–1.0) | < 0.001* |
PT_ED (sec) | 14.7 (13.3–17.4) | 15.6 (14.3–21.1) | 14.3 (13.1–16.8) | < 0.001* |
Temperature_ED (oC) | 35.4 (34.5–36.4) | 35.1 (34.1–35.9) | 35.5 (34.5–36.5) | 0.17 |
SBP_ICU (mmHg) | 117 (101–135) | 115 (95–135) | 118 (104–135) | 0.15 |
Hb_ICU (mmol/L) | 7.4 (6.6–8.1) | 7.3 (6.2–7.8) | 7.4 (6.7–8.2) | 0.09 |
pH_ICU | 7.34 (7.28–7.38) | 7.30 (7.23–7.34) | 7.34 (7.29–7.38) | < 0.001* |
PaCO2_ICU (mmHg) | 41 (36–46) | 43 (38–50) | 41 (36–46) | 0.048* |
BD_ICU (mEq/L) | −4.1 (−6.6–2.1) | −5.5 (−10.0–3.4) | −4.0 (−5.9–1.9) | < 0.001* |
Temperature_ICU (oC) | 35.1 (34.4–35.9) | 35.1 (34.1–35.7) | 35.2 (34.4–36.0) | 0.15 |
UO_ICU (ml) | 145 (80–300) | 165 (80–363) | 140 (80–300) | 0.32 |
Resuscitation parameters | ||||
Crystalloids ≤ 8h (L) | 5.3 (3.9–7.2) | 6.2 (3.9–6.7) | 5.2 (3.9–6.7) | 0.003* |
PRBC ≤ 8h (U) | 3 (0–7) | 5 (2–13) | 3 (0–6) | 0.003* |
FFP ≤ 8h (U) | 3 (0–6) | 4 (1–10) | 2 (0–6) | 0.003* |
PLT ≤ 8h (U)# | 0 (0–1) | 1 (0–2) | 0 (0–1) | 0.002* |
Crystalloids ≤ 24h (L) | 8.6 (6.7–11.2) | 11.3 (8.0–13.6) | 8.3 (6.6–10.6) | < 0.001* |
PRBC ≤ 24h (U) | 4 (0–8) | 5 (1–13) | 3 (0–7) | 0.046* |
PRBC ≥ 10 units ≤ 24h | 57 (18) | 19 (32) | 38 (15) | 0.002* |
FFP ≤ 24h (U) | 4 (0–8) | 5 (0–14) | 3 (0–8) | 0.03* |
PLT ≤ 24h (U)# | 0 (0–2) | 1 (0–3) | 0 (0–1) | 0.03* |
TXA ≤ 24h | 244 (78) | 46 (78) | 198 (78) | 1.0 |
Outcome parameters | ||||
Ventilator days | 6 (2–11) | 6 (2–13) | 6 (2–11) | 0.69 |
ICU LOS (days) | 7 (3–13) | 6 (2–13) | 7 (3–14) | 0.24 |
H-LOS (days) | 22 (12–34) | 7 (2–13) | 25 (17–36) | < 0.001* |
MODS | 51 (16) | 18 (31) | 33 (13) | 0.003* |
ARDS | 12 (4) | 2 (3) | 10 (4) | 1.0 |
Infectious complications | 140 (45) | 17 (29) | 123 (48) | 0.006* |
Thrombo-embolic complications | 34 (11) | 4 (7) | 30 (12) | 0.36 |