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Table 1 Demographics, injury characteristics and outcome for adult patients with isolated moderate-to-severe traumatic brain injury primarily admitted to acute care trauma hospitals, by transfer status to a neurotrauma center

From: Care pathways and factors associated with interhospital transfer to neurotrauma centers for patients with isolated moderate-to-severe traumatic brain injury: a population-based study from the Norwegian trauma registry

 

All patients (n = 1735)

Not transferred (n = 1043)

Transferred (n = 692)

P valuea

Missing

Patient age, median (IQR)

67 (49–80)

72 (53–84)

60 (42–71)

< 0.001

0.0%

Sex

   

< 0.001

0.0%

 Female

563 (32.4)

387 (37.1)

176 (25.4)

 

 Male

1172 (67.6)

656 (62.9)

516 (74.6)

 

Preinjury ASA-PS

   

0.015

3.7%

 Normal health

572 (34.3)

334 (32.9)

238 (36.4)

 

 Mild systemic disease

641 (38.4)

392 (38.6)

249 (38.1)

 

 Severe systemic disease

423 (25.3)

276 (27.2)

147 (22.5)

 

 Severe systemic disease that is a constant threat to life

34 (2.0)

14 (1.4)

20 (3.1)

 

Mechanism of injury

   

0.009

5.0%

 Traffic-related

244 (14.8)

154 (15.3)

90 (14.0)

 

 Low-energy fallb

834 (50.6)

536 (53.2)

298 (46.4)

 

 High-energy fall

404 (24.5)

227 (22.5)

177 (27.6)

 

 Other

167 (10.1)

90 (8.9)

77 (12.0)

 

Injury site’s centrality class c

   

0.693

6.3%

 Major urban Norway

483 (29.7)

291 (29.0)

192 (30.9)

 

 Minor urban Norway

938 (57.7)

587 (58.5)

351 (56.5)

 

 Rural Norway

204 (12.6)

126 (12.5)

78 (12.6)

 

Distance between ACTH and NTC d

   

0.376

0,0%

 Kilometers, median (IQR)

103 (55–220)

103 (55–220)

123 (61–195)

 

NISS, median (IQR)

22 (14–30)

17 (14–25)

29 (22–41)

< 0.001

0.0%

Maximum AIS Head score

   

< 0.001

0.0%

 3

862 (49.7)

628 (60.2)

234 (33.8)

 

 4

402 (23.2)

249 (23.9)

153 (22.1)

 

 5-6e

471 (27.2)

166 (15.9)

305 (44.1)

 

GCS score on admission

   

< 0.001

17.5%

 14–15

933 (65.2)

746 (73.4)

187 (45.2)

 

 9–13

269 (18.8)

144 (14.2)

125 (30.2)

 

 <9

229 (15.6)

127 (12.5)

102 (24.6)

 

Type of head injury f

    

0.0%

 Subdural hematoma

1120 (64.6)

635 (60.9)

485 (70.1)

< 0.001

 

 Skull fracture

818 (47.1)

391 (37.5)

427 (61.7)

< 0.001

 

 tSAH

742 (42.8)

367 (35.2)

375 (54.2)

< 0.001

 

 Contusion

731 (42.1)

349 (33.5)

382 (55.2)

< 0.001

 

 Epidural hematoma

191 (11.0)

53 (5.1)

138 (19.9)

< 0.001

 

 Brain stem

62 (3.6)

17 (1.6)

45 (6.5)

< 0.001

 

Highest level of in-hospital care g

   

< 0.001

1.1%

 General ward

373 (21.7)

342 (33.3)

31 (4.5)

 

 CCU/HDU

1295 (75.5)

662 (64.5)

633 (91.7)

 

 Other

48 (2.8)

22 (2.1)

26 (3.8)

 

30-day mortality

265 (15.7)

176 (17.4)

89 (13.1)

0.019

2.5%

  1. Abbreviations: ACTH, Acute care trauma hospital; AIS, Abbreviated Injury Scale; ASA-PS, American Society of Anesthesiologists physical status; CCU/HDU, Critical care or high-dependency unit; GCS, Glasgow Coma Scale; IQR, Interquartile range; NISS, New Injury Severity Score; NTC, Neurotrauma Center; tSAH, Traumatic subarachnoid hemorrhage
  2. Data reported as n (%) unless stated otherwise
  3. aP values were derived from the Mann-Whitney U test for continuous data and chi-squared test for categorical data, testing the null hypothesis of no difference between strata
  4. b Low-energy fall is defined as a fall from standing or up to one meter
  5. c Centrality class according to Statistics Norway 2017 Centrality Index
  6. d Driving distance between the ACTH where the patient was primarily referred and the corresponding NTC according to the national trauma plan
  7. e A total of five patients had AIS Head scores of 6 and none were transferred
  8. f Type of head injury was derived from AIS codes. More than one type of head injury may be described per patient, including injuries with AIS Head scores < 3 for those who had at least one AIS Head score ≥ 3
  9. g Highest level of in-hospital care reported at the definitive care hospital level. Other includes emergency department, operating room, and other