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Table 1 Population characteristics stratified by need for (continued) transfusion of blood products in hospital

From: Predictive clinical utility of pre-hospital point of care lactate for transfusion of blood product in patients with suspected traumatic haemorrhage: derivation of a decision-support tool

 

All patients (n = 306)

In-hospital transfusion (n = 126)

No In-hospital transfusion (n = 142)

p value

Demographics

Age, years (SD)

47.4 [21.6]

47.5 [21.7]

47.4 [21.6]

.73

Male, (n [%])

197 [73.5]

90 [71.4]

107 [75.4]

.57

Female, (n [%])

71 [23.2]

36 [28.6]

35 [24.6]

 

Missing, (n [%])

38 [3.3]

   

Mechanism descriptors (n, %)

RTC

162 [52.9]

91 [72.2]

71 [55.6]

< 0.001

Accidental Injury

20 [6.5]

16 [12.7]

4 [2.8]

Intentional Self Harm

25 [8.1]

9 [7.14]

16 [11.3]

Assault

19 [6.2]

8 [6.3]

18 [12.6]

Fall

30 [9.8]

4 [3.2]

26 [18.4]

Cyclist

5 [1.6]

0 [0]

5 [3.5]

Motorcyclist

18 [5.9]

4 [3.2]

14 [9.9]

Other

8 [2.6]

2 [1.6]

6 [4.2]

Presenting physiology

TCA (n [%])

15 [8.5]

14 [10.4]

1 [9.2]

< 0.001

HR (mean [SD])

missing

91 [25.1]

17

106 [32.6]

98 [29.6]

< 0.001

SBP (mean [SD])

missing

106 [34.4]

20

88 [31.8]

120 [29.5]

< 0.001

Shock Index (mean [SD])

missing

1.0 [0.5]

27

1.3 [0.6]

0.8 [0.3]

< 0.001

GCS (median [IQR])

missing

13 [6–15]

3

10 [3–14]

0

14 [10–15]

3

< 0.001

P-LACT

Presenting P-LACT (mmol/L) (mean [SD])

missing

2.9 [2.4]

84

4.60 [2.4]

3.5 [3.5]

< 0.001

Pre-hospital interventions

PHEA (n [%])

101 [36.9]

64 [50.4]

37 [25.5]

< 0.001

Pre-hospital Code Red

103 [39.9]

89 [70.4]

14 [9.2]

< 0.001

Pre-hospital Transfusion

124 [49.0]

100 [79.2]

24 [16.3]

< 0.001

PRBC (units, %) mode [range]

 

0 [4]

0 [3]

< 0.001

FDP (units, %) mode [range]

 

1 [4]

0 [4]

< 0.001

PRBC units (n, %)

 0 units

169 [60.8]

40 [31.2]

129 [91.5]

.68

 1 units

44 [17.0]

37 [29.6]

7 [4.3]

 2 units

28 [10.1]

24 [19.2]

4 [2.8]

 3 units

18 [7.8]

16 [12.8]

2 [1.4]

 4 units

9 [4.2]

9 [7.2]

0 [0]

Clinical outcome

Hospital lactate (mmol/L)

Missing (n [%])

3.4 [2.6]

204 [66.6]

4.4 [3.0]

2.00 [1.0]

< 0.001

ISS (mean [SD])

Missing (n [%])

14 [17–41]

82 [27.8]

33 [23.5–43.0]

22 [13–33]

< 0.001

ICU Length of stay (mean [SD])

Missing (n [%])

3 [.00–11.7]

82 [27.8]

4.5 [1.00–16.75]

2 [.0–8.00]

< 0.001

Hospital Length of stay (mean [SD])

Missing (n [%])

16 [5.7 – 31.2]

84 [27.45]

18 [3–42]

14 [7–26.0]

.50

Survival to discharge

Missing (n [%])

144 (47.1)

97[31.7]

57 [44.8]

87 [61.0]

< 0.001

  1. Demographics, proxy injury and physiological parameters: HR heart rate, SBP systolic blood pressure, SI shock index, GCS Glasgow Coma Scale, PHEA pre-hospital emergency anaesthesia, PRBC packed red blood cells, FDP freeze-dried plasma, P-LACT pre-hospital lactate, ICU Intensive Care Unit