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Table 3 Overview of analysed biomarkers

From: Can we rely on out-of-hospital blood samples? A prospective interventional study on the pre-analytical stability of blood samples under prehospital emergency medicine conditions

Biomarkers in alphabetic order

Unit

Number of measurements

Mean of differences

CI mean

Upper limit of agreement

CI upper limit of agreement

Lower limit of agreement

CI lower limit of agreement

Alpha-HBDH (Clotting Activator)

U/l

133

−1,143

[−6.38; 4.095]

59,928

[50.857;69]

−62,214

[−71.286; −53.142]

Alpha-HBDH (Lithium Heparin)

U/l

133

6,474

[2.725; 10.223]

50,189

[43.695;56.682]

−37,241

[−43.735; −30.748]

Antithrombin III

U/l

128

−0,156

[−0.858; 0.546]

7,869

[6.653;9.085]

−8,182

[−9.397; −6.966]

aPTT

sec.

128

−0,049

[−0.318; 0.22]

3,029

[2.563;3.495]

−3,128

[−3.594; −2.661]

Calcium

mmol/l

129

0,004

[−0.001; 0.009]

0,063

[0.054;0.072]

−0,055

[−0.064; −0.046]

Chloride

mmol/l

131

−0,191

[−0.424; 0.042]

2,505

[2.102;2.909]

−2,887

[−3.29; −2.483]

Creatin Kinase (CK) (Clotting Activator)

U/l

133

0,15

[−0.977; 1.278]

13,301

[11.348;15.254]

−13

[−14.954; −11.047]

Creatin Kinase (CK) (Lithium Heparin)

U/l

133

−0,895

[−2.044; 0.255]

12,509

[10.518;14.5]

−14,298

[−16.289; −12.307]

Creatinine

mg/dl

134

−0,006

[−0.01; −0.001]

0,046

[0.039;0.054]

−0,058

[−0.066; −0.05]

Fibrinogen

mg/dl

128

2,438

[−3.973; 8.848]

75,743

[64.639;86.847]

−70,868

[−81.972; −59.764]

Free Haemoglobin (Clotting Activator)

mg/l

132

−0,606

[−2.528; 1.316]

21,718

[18.389;25.047]

−22,93

[−26.259; −19.601]

Free Haemoglobin (Lithium Heparin)

mg/l

128

−0,062

[−1.729; 1.604]

18,992

[16.106;21.878]

−19,117

[−22.003; −16.231]

Glutamic Oxaloacetic Transaminase (GOT/AST)

U/l

134

0,604

[0.207; 1.001]

5,252

[4.564;5.939]

−4,043

[−4.73; −3.355]

Haemoglobin

g/dl

131

0,005

[−0.033; 0.044]

0,45

[0.383;0.517]

−0,439

[−0.506; −0.373]

INR

 

128

−0,003

[−0.009; 0.002]

0,059

[0.05;0.069]

−0,066

[−0.075; −0.056]

Leukocytes

109/l

131

−0,005

[−0.067; 0.057]

0,713

[0.605;0.82]

−0,722

[−0.829; −0.615]

Myoglobin

μg/l

134

−2,336

[−4.019; −0.652]

17,367

[14.452;20.283]

−22,039

[−24.954; −19.123]

Potassium

mmol/l

129

0,017

[−0.013; 0.046]

0,355

[0.304;0.406]

−0,321

[−0.372; −0.27]

Sodium

mmol/l

129

0,227

[−0.011; 0.465]

2,956

[2.544;3.368]

−2,502

[−2.914; −2.09]

Thrombocytes

109/l

131

6,443

[4.765; 8.12]

25,85

[22.944;28.755]

−12,964

[−15.869; −10.059]

Troponin I (Lithium Heparin)

μg/l

134

−0,009

[−0.016; −0.002]

0,072

[0.06;0.084]

−0,091

[−0.103; −0.079]

  1. Means of differences, standard deviations and confidence intervals between Groups of immediate analysis and analysis after mechanical stress and time delay. The estimated means of differences are always negligible with a small 95%-CI, i.e. mechanical stress does not produce a systematic bias but only random inaccuracy
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Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine

ISSN: 1757-7241