Illustrative comparative risks* (95% CI) | ||||
---|---|---|---|---|
Outcomes | Assumed risk | Corresponding risk | Relative effect (95% CI) | GRADE |
NWBCT | WBCT | |||
Mortality | 231 per 1000 | 190 per 1000 | OR 0.66 | ⊕⊕⊝⊝ low1,2 |
(180- 200) | (0.52 - 0.85) | |||
ED Time | The mean ED time ranged across control groups from 82 to 144.7 min | The mean ED time in the intervention groups was 27.58 lower (43.04 to 12.12 lower) | NR | ⊕⊕⊝⊝ low1,2,3,4 |
ICU-LOS | The mean ICU-LOS ranged across control groups from 1 to 16.8 days | The mean ICU-LOS in the intervention groups was 0.95 higher (0.08 Lower to 1.98 higher) | NR | ⊕⊕⊝⊝ very low1,2,5 |
Ventilation Time | The mean duration of mechanical ventilation ranged across control groups from 0 to 14.3 days | The mean duration of mechanical ventilation in the intervention groups was 0.96 higher (0.32 to 1.61 higher) | NR | ⊕⊕⊝⊝ very low1,2,6 |
Hospital-LOS | The mean Hospital- LOS ranged across control groups from 8.5 to 32.5 days | The mean Hospital-LOS in the intervention groups was 0.56 higher (0.03 Lower to 1.15 higher) | NR | ⊕⊕⊝⊝ very low1,2,7 |
MODS/MOF | 284 per 1000 | 363 per 1000 | OR 1.44 | ⊕⊕⊝⊝ very low1,8 |
(348 to 379) | (1.35 to 1.54) |