Study period 2001-3 | Study period 2005-7 | P-value1 | ||
---|---|---|---|---|
n | 21 | 45 | ||
Age | years | 50 (35-69) | 40 (28-52) | 0.106 |
Gender | male | 16 (76%) | 32 (71%) | 0.666 |
ISS | score | 26 (17-34) | 27 (19-36) | 0.694 |
Mortality | deceased | 7 (37%) | 17 (39%) | 0.893 |
Hemoglobin | mmol/l | 5.7 (4.6-6.8) | 6.7 (5.6-7.6) | 0.066 |
Platelet count | < 150*109/l | 8 (53%) | 17 (44%) | 0.520 |
APTT | > 35 s | 9 (60%) | 24 (62%) | 0.917 |
INR | > 1.2 | 11 (73%) | 21 (54%) | 0.192 |
Time to first blood product | min | 28 (22-65) | 3 (0-23) | < 0.001 |
RBC 0-6 h | n | 12 (12-24) | 20 (14-30) | 0.0394 |
RBC total | n | 14 (12-23) | 20 (14-30) | 0.0933 |
FFP 0-6 h | n | 5 (4-10) | 14 (10-20) | < 0.001 |
FFP total | n | 6 (4-12) | 14 (10-21) | < 0.001 |
PLT 0-6 h | n | 0 (0-1) | 6 (4-8) | < 0.001 |
PLT total | n | 0 (0-2) | 6 (4-8) | < 0.001 |
FFP:RBC 0-6 h | ratio | 0.33 (0.16-0.53) | 0.71 (0.59-0.85) | < 0.001 |
FFP:RBC total | ratio | 0.36 (0.24-0.59) | 0.74 (0.61-0.85) | < 0.001 |
PLT:RBC 0-6 h | ratio | 0 (0-0.05) | 0.29 (0.20-0.37) | < 0.001 |
PLT:RBC total | ratio | 0 (0-0.05) | 0.29 (0.20-0.35) | < 0.001 |
PLT:FFP 0-6 h | ratio | 0 (0-0.10) | 0.40 (0.36-0.43) | < 0.001 |
PLT:FFP total | ratio | 0 (0-0.13) | 0.40 (0.35-0.46) | < 0.001 |