Critical Care in the Emergency Department: An assessment of the length of stay and invasive procedures performed on critically ill ED patients

Introduction Critically ill patients commonly present to the ED and require aggressive resuscitation. Patient transfer to an ICU environment in an expedient manner is considered optimal care. However, this patient population may remain in the ED for prolonged periods of time. The goal of this study is to describe the ED length of stay, and the invasive procedures performed in critically ill ED patients. Methods This is a retrospective medical record review of all patients who presented to the study center over a 1 year period. Patient demographic data, in addition to the times of ED presentation and ICU admission were recorded. Invasive procedures performed in the pre-hospital, ED and the initial 24 hours of ICU care were also recorded. Results Overall, 178 patients' required direct admission to an ICU from the ED, with a mortality rate of 21.9%. The median LOS in the ED for critically ill patients requiring ICU admission was 4.9 h (mean 6.5 h, range 1.4-28.2 h). Seventy percent of patients (125,178, 70.2%) required endotracheal intubation with the majority (118/125, 94.4%) being performed in the ED (80/125, 64.0%) or the prehospital setting (38/125, 30.4%). Central venous access was obtained in 56/178 patients (31.5%), with 17.9% (10/56) completed in the ED. Similarly, arterial catheters were inserted in 99/178 patients (55.6%) with 14.1% (14/99) inserted in the ED. Conclusion Critically ill patients are managed in the emergency department for a significant length of time. Although the majority of airway intervention occurs in the prehospital setting and ED, relatively few patients undergo invasive procedures while in the emergency department.

(page number not for citation purposes) to the ED and are managed for prolonged periods of time despite requiring admission to an intensive care unit (ICU). [1,3,[7][8][9][10][11] Data on the management of critically ill patients in the ED is incomplete. The primary objective of this study is to determine the length of stay of critically ill patients receiving care in a tertiary care adult emergency department. The secondary objective is to describe the invasive procedures performed in the ED phase of care.

Methods
This study was a retrospective chart review that included all patients presenting to the Queen Elizabeth II Health Sciences Center in Halifax, Nova Scotia, Canada and admitted directly to the one of two mixed medical/surgical/neurosurgical intensive care units from the ED over a one year period (January 1, 2002 through December 31, 2002). The Queen Elizabeth II Health Sciences Center ED is an adult (age ≥17 years) tertiary care ED with approximately 70,000 patient visits per year. Inclusion criteria was any patient who was assessed and managed by the ED physician and was subsequently admitted to one of two Intensive Care Units. Exclusion criteria included patients under 17 years, patients transferred to the ED from another hospital, patients managed by the multi-disciplinary trauma team (and therefore may not have been managed by an ED physician), or patients requiring surgical intervention prior to ICU admission.
Patients were identified by manual review of both ED and ICU admission records. A standardized electronic data abstraction form was developed by the investigators. Approximately 10% of data abstraction was reviewed by both investigators to ensure data reliability. Any discrepancy in data was resolved by consensus. All available data in the medical record was recorded into the database. Missing data that was unavailable in the medical record were also noted and data analysis was based on available data. Procedures not recorded in the medical record were recorded as not being preformed.
Data was collected for 3 phases of medical care: the prehospital phase, ED phase and the initial 24 hours after ICU admission and included patient demographics, ED diagnosis, Canadian Triage Acuity score (CTAS), critical care procedures performed, and the ED and hospital LOS. CTAS is a triage tool developed in conjunction with the Canadian Association of Emergency Medicine to enable ED patient care prioritization, and ranges from CTAS 1 (critically ill) to CTAS 5 (non-emergent). [12] The emergency department length of stay (LOS) was defined as the time from ED triage to transfer to ICU, and hospital LOS was defined as the time from hospital admission to patient discharge. The critical care procedures recorded were endotracheal intubation (ETI), central venous catheter (CVC) and arterial cannulation (AC), and chest tubes insertion.
The data was analyzed using descriptive statistics. Mean and median values and frequencies were calculated. The study was approved by the Research Ethics Board of the Queen Elizabeth II Health Sciences Center, Halifax, Nova Scotia, Canada.

Results
During the study period, 68,765 patients presented to the ED and 178 patients met inclusion criteria (ICU admission rate 0.26%). The median age of the study population was 55 years and 59.6% were male ( Table 1). The in-hospital mortality rate of the study population was 21.9% (39/178). Patients who survived (139/178) were discharged home (111/178, 62.3%) or to long term care or other facilities (26/178, 14.6%).
The majority of patients received at least one invasive procedure in the ED (

Discussion
We have found that critically ill patients in our study were managed in the ED for 4.9 hours prior to transfer to an ICU. In addition, although the majority of emergent airway management is provided in the ED and pre-hospital setting, other invasive procedures such as central venous catheterization and arterial cannualtion were more commonly preformed after transfer to an ICU setting.
The management of critical illness in the emergency department occurs at a crucial phase in a patient's care, when intervention may significantly improve outcome and survival. [4,5,13] Early and aggressive care for critically ill patients is believed to optimize patient outcomes, as the stabilization of physiological derangements reduces the progression of multi-organ dysfunction. [13][14][15] However, the ED may not be the optimal location for prolonged or ongoing provision of critical care, as physicians and other health care members have divided priorities in the management of other ED patients. ED physicians and nurses may not possess the skill sets to allow for the provision of optimal care beyond the acute resuscitation. In addition, some ED's may not have the resources available to provide ongoing or prolonged care for critically ill patients, and therefore the rapid transport of patient to an ICU environment is desirable.
The median LOS of patients in our study are similar to previous reports, which range from 4.4-6.2 hours. [1,3,6,7,12] Little data is available for countries other than the USA, and therefore this study highlights a potential global issue. Emergency Department LOS of critically ill patients is likely multifactorial and may include time required for ED diagnosis, resuscitation and necessary investigations. However, other factors such as ED overcrowding, ICU resource availability and local practice patterns may affect ED LOS. Further work focusing on modifiable factors contributing to prolonged ED LOS of critically ill patients would further clarify this issue.
This study has also demonstrated that some invasive procedures are performed frequently in the ED while others are not completed until after admission to the ICU. It is interesting that the majority of airway interventions occurred in the ED prior to ICU admission (94.4%), however relatively few patients underwent invasive procedures such as CVC or AC insertion in the ED. In addition, invasive procedures not performed in the ED were often performed early in the ICU admission. Other studies have reported variable procedure completion rates in the ED, as EETI rates have ranged from 13.3-30.8% [8,10,11,13], CVC rates 3.9-26%; and arterial catheter rates 0.0-14.8% [8,10,11] It is possible that some procedures may have been delayed until transfer, which may indicate that life saving therapy was delayed.
Our study highlights several important issues, namely the prolonged length of stay of critically ill patients in the ED and an apparent disparity in invasive procedures employed in the ED. Current evidence suggests that aggressive resuscitation and interpretation of physiologic data in critically ill patients is beneficial in patient outcomes, and may result in a reduction in ICU admissions. [4,13,15] It is unclear if the management provided for patents in this study was optimal, or if a reduction in the LOS or additional invasive procedures performed in the ED  Note: classification is based on primary physiological system affected by patient illness. The majority of patients had multiple physiologic system derangement. @ Level of consciousness # Intra-cranial hemorrhage $ Acute coronary syndrome % Pulmonary embolus & Chronic Obstructive Pulmonary Disease * Traumatic Brain Injury + Diabetic ketoacidosis = Other: epistaxis, chart incomplete (2), suicide attempt, supraglotitis swelling, neck haematoma ! Reason for ICU admission not stated in chart, or multifactorial in nature

Limitations
There are several limitations to our study, as this is a single center retrospective medical record review. Although we are confident that all patients admitted to the ICU during the study phase were identified, chart documentation was not complete for some of the variables examined. Despite this, we feel that the ED LOS and procedures completed which are reported are valid. Finally, the number of patients included in this study was relatively small and trauma patients, cardiac patients and patients requiring operative intervention prior to ICU admission were excluded, which does not allow interpretation of our data in this patient population.

Conclusion
Critically ill patients are managed in the emergency department for a significant length of time. Although the majority of airway intervention occurs in the prehospital and ED setting, relatively few patients undergo invasive procedures while in the emergency department. Further research on the importance of ED LOS of critically ill patients is suggested.