Fig. 5From: Fluid resuscitation with balanced crystalloids versus normal saline in critically ill patients: a systematic review and meta-analysisTrial sequential analysis for mortality at the longest follow-up. TSA used estimates of 27.2% for baseline mortality, 5% for relative risk reduction, 5% for alpha and 80% for power. The sample size reached required information size, but Z-curve not crossed conventional boundary and TSA boundaryBack to article page