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Table 2 Characteristics of MFD-C patients according to critical parameters at admission and fibrinogen administration at 24-h

From: Which injured patients with moderate fibrinogen deficit need fibrinogen supplementation?

Study group

Shock index > 1.0

Hemoglobin < 110 g L−1

Base deficit > 5.0 mEq L−1

Fibrinogen administration

No

Yes

No

Yes

No

Yes

No

Yes

N

211 (80)

54 (20)

195 (74)

67 (26)

133 (56)

106 [44]

144 (54)

122 (46)

Demographic data

 Age (years)

31 [22–50]

28 [22–46]

28 [21–45]

42* [25–65]

29 [21–49]

35 [23–50]

33 [22–50]

28 [22–46]

 ISS

25 [18–33]

29 [17–38]

24 [17–30]

27* [18–41]

24 [17–29]

29* [22–38]

24* [17–29]

27 [19–36]

Prehospital parameters

 GCS

14 [8–15]

14 [7–15]

15 [9–15]

14* [7–15]

14 [9–15]

13* [6–15]

14 [10–15]

14 [6–15]

 SBP (mmHg)

122 [104–137]

115 [96–130]

123 [108–138]

110* [80–132]

125 [108–140]

114* [94–131]

123 [105–138]

118 [100–134]

 Fluids (mL)

1000 [500–150]

1375* [1000–1563]

1000 [500–1500]

1250* [1000–1500]

750 [500–1250]

1250* [750–1500]

1000 [500–1500]

1000 [600–1500]

Admission parameters

 SBP (mmHg)

121 [108–135]

90* [77–102]

120 [103–134]

101* [87–123]

120 [107–135]

111* [90–132]

116 [101–133]

116 [95–134]

 Shock Index

0.7 [0.6–0.9]

1.3* [1.1–1.5]

0.8 [0.6–1.0]

0.9* [0.7–1.1]

0.7 [0.6–0.9]

0.9* [0.7–1.1]

0.8* [0.6–1.0]

0.8 [0.7–1.1]

 Base deficit (mEq L−1]

4.3 [2.3–6.1]

6.9* [4.6–10.8]

3.8 [2.3–5.8]

6.9* [4.7–8.9]

2.8 [1.9–3.9]

7.3* [5.9–9.2]

3.8* [2.0–6.1]

5.4 [3.6–7.8]

 Hemoglobin (g L−1)

127 [113–140]

115* [93–126]

129 [121–141]

94* [86–106]

127 [116–141]

119* [101–131]

127* [115–140]

120 [101–133]

 PTratio

1.2 [1.1–1.3]

1.2* [1.1–1.4]

1.1 [1.1–1.2]

1.3* [1.2–1.4]

1.1 [1.1–1.2]

1.2* [1.1–1.3]

1.1* [1.1–1.2]

1.2 [1.1–1.3]

 Fibrinogen (g L−1)

1.8 [1.6–1.9]

1.7* [1.6–1.8]

1.8 [1.6–1.9]

1.8 [1.6–1.9]

1.8 [1.6–1.9]

1.7* [1.6–1.8]

1.8* [1.7–1.9]

1.7 [1.6–1.8]

 Platelet (109 L−1)

219 [184–258]

226 [183–290]

225 [188–271]

208* [154–246]

221 [188–258]

213 [175–277]

225 [189–271]

210 [179–255]

Red blood cell (unit)

0.0 [0.0–0.0]

1.5* [0.0–3.0]

0.0 [0.0–0.0]

2.0* [0.0–4.0]

0.0 [0.0–0.0]

0.0* [0.0–2.0]

0.0* [0.0–0.0]

1.0 [0.0–3.0]

Fibrinogen concentrate

 (g)

0.0 [0.0–0.0]

1.5* [0.0–3.0]

0.0 [0.0–0.0]

2.0* [0.0–3.0]

0.0 [0.0–2.0]

1.5* [0.0–3.0]

–

3.0 [1.5–3.0]

 N (%)

90 (43)

32* (59)

78 (40)

42* (63)

47 (35)

63* (59)

–

–

  1. Data are expressed as count (percentage) or median [interquartile range]
  2. SBP systolic blood pressure, ISS injury severity score, PTratio prothrombin time ratio
  3. *p < 0.05 for the difference between yes versus no.