Table 1 Demographic and injury characteristics of patients for whom Clauss fibrinogen level was determined at admission

Fibrinogenemia (g L⁻¹)

< 1.50

1.51–1.99

> 1.99

 N

980

158 (16)

266 (27)

556 (57)

Demographic data

 Age (years)

41 [25–57]

38 [24–53]

31 [22–50]

46 [28–60]

 Sex male

745 (76)

118 (75)

207 (78)

420 (76)

 Blunt Trauma

918 (94)

150 (95)

248 (93)

520 (94)

 ISS

25 [17–33]

38 [28–50]

25 [18–33]

22 [16–29]

 Mortality at discharge

188 (19)

81 (51)

43 (16)

64 (12)

Prehospital parameters

 GCS

14 [6–15]

5 [3–14]

14 [8–15]

14 [9–15]

 SBP (mmHg)

120 [100–140]

95 [60–123]

120 [100–136]

127 [110–144]

 Shock Index

0.7 [0.6–1.0]

1.1 [0.7–1.6]

0.8 [0.6–1.0]

0.7 [0.6–0.8]

 Fluids (mL)

850 [500–1250]

1500 [1000–2213]

1000 [500–1500]

750 [350–1000]

 Vasopressor

200 (20)

89 (56)

41 (16)

70 (13)

Admission parameters

 SBP (mmHg)

118 [100–136]

101 [73–124]

115 [99–133]

122 [108–140]

 Shock Index

0.7 [0.6–0.9]

1.0 [0.7–1.3]

0.8 [0.6–1.0]

0.7 [0.6–0.8]

 HemoCue < 110 g L⁻¹

248 (26)

102 (66)

67 (26)

79 (15)

 Lactate (mmol L⁻¹)

2.3 [1.5–3.7]

4.4 [2.6–7.8]

2.4 [1.7–3.5]

2.0 [1.3–2.9]

 Base deficit (mEq L⁻¹)

4.6 [2.2–7.5]

10.7 [6.3–16.2]

4.7 [2.6–7.0]

3.5 [1.4–5.7]

 Hemoglobin (g L⁻¹)

126 [109–139]

94 [78–116]

126 [110–137]

132 [119–143]

 PT_ratio

1.1 [1.1–1.3]

1.6 [1.3–2.2]

1.2 [1.1–1.3]

1.1 [1.0–1.1]

 Fibrinogen (g L⁻¹)

2.1 [1.7–2.6]

1.0 [0.6–1.3]

1.8 [1.6–1.9]

2.5 [2.2–3.0]

 Platelet (10⁹ L⁻¹)

214 [179–259]

173 [121–204]

220 [183–266]

225 [190–268]

Blood products [24 h]

 Fibrinogen concentrate (g)

0.0 [0.0–1.5]

4.5 [3.0–6.0]

0.0 [0.0–3.0]

0.0 [0.0–0.0]

 Red blood cell (unit)

0 [0–2]

3 [1–6]

0 [0–2]

0 [0–0]

 Fresh frozen plasma (unit)

0 [0–0]

1 [0–4]

0 [0–0]

0 [0–0]

 Platelet (unit)

0 [0–0]

0 [0–3]

0 [0–0]

0 [0–0]

TXA first 3 h*

679 (70)

137 (87)

225 (85)

317 (57)