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Table 2 Components and scores of established scoring systems and most promising trigger factor iterations

From: Identification and validation of objective triggers for initiation of resuscitation management of acutely ill non-trauma patients: the INITIATE IRON MAN study

 

qSOFA (0–3)

NEWS (0–20)

Iteration 1

Iteration 2

Iteration 3

Positive if:

 ≥ 2 points

 ≥ 7 points*

 ≥ 2 points or D alone

qSOFA ≥ 2 or any of the following

Any of the following

A/B

RR > 21/min (1)

RR, breaths per min (0–3):

0, 12–20

1, 9–11

2, 21–24

3, ≥ 25 or < 8

SpO2, % (0–3):

0, > 96

1, 94–95

2, 92–93

3, < 91

O2 supplement (0–2):

No (0)

Yes (2)

RR > 25/min or SpO2 < 90% (1)

SpO2 < 85%

SpO2 < 90%

C

SBP ≤ 100 mmHg (1)

HR, beats per min (0–3):

0, 51–90

1, 41–50 or 90–110

2, 111–130

3, 131

SBP, mmHg (0–3):

0, 111–219

1, 101–110

2, 91–100

3, ≥ 220 or ≤ 90

SBP < 100 mmHg (1)

Lactate ≥ 3 mmol/l (1)

SBP < 85 mmHg

SBP < 90 mmHg or

D

Altered mentation (1)

AVPU Scale Alert (0), reacting to voice or pain or unresponsive (3)

GCS < 15 (1)

GCS < 15

GCS < 15

E

n.a

Body temperature, °C (0–3):

0, 36.1–38

1, 35.1–36 or 38.1–39

2, > 39.1

3, ≤ 35

n.a

n.a

n.a

  1. AVPU, Alert, Verbal, Pain, Unresponsive; GCS, Glasgow Coma Scale; HR, heart rate; n.a., not available; NEWS, National Early Warning Score; qSOFA, Quick Sequential Organ Failure Assessment Score; RR, respiratory rate; SBP, systolic blood pressure; SpO2, peripheral oxygen saturation
  2. *The NEWS score (0–20 points) recommends “emergency assessment by a clinical team/critical care outreach team with critical-care competencies” at ≥7 points. Accordingly, a NEWS ≥7 cut-off was considered as positive