|
For prediction of MACE in the whole population (n = 533 patients*)
|
The 4 high-risk clinical items
|
Initial positive troponin assay
|
Troponin rise
|
|---|
|
Sensitivity, % (95% CI)
|
100.0 (54.1–100)
|
83.3 (35.9–99.6)
|
33.3 (4.3–77.7)
|
|
Specificity, % (95% CI)
|
76.6 (73.4–79.6)
|
97.7 (96.1–98.8)
|
99.2 (98.3–99.7)
|
|
Predictive value, % (95% CI)
| | | |
|
Positive
|
4.3 (3.8–4.9)
|
29.3 (17.5–44.6)
|
24.9 (7.7–56.9)
|
|
Negative
|
100.0 (99.9–100.0)
|
99.9 (99.2–99.9)
|
99.5 (99.1–99.7)
|
|
Likelihood ratio (95% CI)
| | | |
|
Positive
|
4.6 (4.1–5.2)
|
36.6 (18.8–71.1)
|
43.3 (10.8–172.7)
|
|
Negative
|
0
|
0.17 (0.03–1.02)
|
0.7 (0.4–1.2)
|
|
Accuracy, % (95% CI)
|
76.9 (73.7–79.8)
|
97.6 (95.9–98.7)
|
98.7 (97.7–99.4)
|
|
For prediction of MACE in high-risk population (= 153 patients*)
|
Initial positive troponin assay
|
Troponin rise
|
|---|
|
Sensitivity, % (95% CI)
|
83.3 (35.9–99.6)
|
33.3 (4.3–77.7)
|
|
Specificity, % (95% CI)
|
95.2 (90.4–98.1)
|
97.2 (93.5–99.1)
|
|
Predictive value, % (95% CI)
| | |
|
Positive
|
41.7 (24.2–61.5)
|
28.5 (8.8–62.4)
|
|
Negative
|
99.3 (95.9–99.9)
|
97.7 (96.1–98.7)
|
|
Likelihood ratio (95%CI)
| | |
|
Positive
|
17.5 (7.8–39.2)
|
11.8 (2.8–49.0)
|
|
Negative
|
0.2 (0.0–1.1)
|
0.7 (0.4–1.2)
|
|
Accuracy, % (95% CI)
|
94.8 (90.0–97.7)
|
95.1 (90.9–97.7)
|
- *Performed in patients with troponin assay
- MACE major adverse cardiac event, 95% CI 95% confidence interval
