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Table 3 Demographics of the subgroups based on beta-blocker exposure prior to and after propensity score matching

From: Beta-blockade is not associated with improved outcomes in isolated severe extracranial injury: an observational cohort study

Variable

Before matching

After matching

BB+

(n = 73)

BB

(n = 625)

p

BB+

(n = 73)

BB

(n = 73)

p

Age, mean [SD] years

69.5 [14.1]

43.2 [18.0]

 < 0.001

69.5 [12.3]

70.2 [14.6]

0.628

Male sex, % (n)

67.1 (49)

80.8 (505)

0.010

67.1 (49)

68.5 (50)

1.000

GCS > 8, % (n)

91.8 (67)

85.6 (535)

0.204

91.8 (67)

84.9 (62)

0.302

SBP < 90 mmHg, % (n)

12.3 (9)

12.3 (77)

1.000

12.3 (9)

13.7 (10)

1.000

Penetrating injury, % (n)

6.8 (5)

12.0 (75)

0.266

6.8 (5)

5.5 (4)

1.000

ISS, mean [SD]

23.7 [7.8]

24.7 [10.9]

0.482

23.7 [12.3]

23.5 [9.8]

0.894

ISS 16–24, % (n)

64.4 (47)

63.8 (399)

1.000

64.4 (47)

71.2 (52)

0.442

ISS 25–49, % (n)

32.9 (24)

32.7 (201)

1.000

32.9 (24)

23.3 (17)

0.210

ISS 50–74, % (n)

2.7 (2)

1.9 (12)

0.650

2.7 (2)

4.1 (3)

1.000

CCI 0, % (n)

8.2 (6)

64.3 (401)

 < 0.001

8.2 (6)

4.1 (3)

0.375

CCI 1, % (n)

13.7 (10)

14.9 (93)

0.924

13.7 (10)

15.1 (11)

1.000

CCI 2, % (n)

17.8 (13)

8.0 (50)

0.011

17.8 (13)

19.2 (14)

1.000

CCI 3, % (n)

17.8 (13)

4.8 (30)

 < 0.001

17.8 (13)

15.1 (11)

0.791

CCI 4, % (n)

15.1 (11)

5.0 (31)

0.002

15.1 (11)

20.5 (15)

0.503

CCI 5, % (n)

12.3 (9)

1.8 (11)

 < 0.001

12.3 (9)

15.1 (11)

0.815

CCI 6, % (n)

4.1 (3)

0.6 (4)

0.028

4.1 (3)

5.5 (4)

1.000

CCI 7, % (n)

2.7 (2)

0.5 (3)

0.088

2.7 (2)

2.7 (2)

1.000

CCI 8, % (n)

6.8 (5)

0.2 (1)

 < 0.001

6.8 (5)

1.4 (1)

0.125

CCI 9, % (n)

1.4 (1)

0 (0)

0.105

6.8 (5)

1.4 (1)

0.125

Surgery required, % (n)

61.6 (45)

75.6 (471)

0.015

53.4 (39)

54.8 (40)

1.000

  1. Patients were matched using propensity score matching. Variables matched included age, injury mechanism, ISS, SBP, CCI and surgery required or not
  2. SD, standard deviation; GCS, Glasgow Coma Scale; SBP, Systolic Blood Pressure; ISS, Injury Severity Score; CCI, Charlson Comorbidity Index