|
Study
|
MTBI
|
Sensitivity
|
|---|
|
ANTONI_2019
|
NA
|
1.85% (0.23–6.53%)
|
|
BATTLE_2017
|
NA
|
2.27% (0.06–12.02%)
|
|
CHENOWETH_2018
|
NA
|
7.11% (3.94–11.64%)
|
|
ERNSTBRUNNER_2016
|
1.05% (0.29–2.66%)
|
1.05% (0.29–2.66%)
|
|
GALLIAZZO_2019
|
1.53% (0.19–5.41%)
|
1.53% (0.19–5.41%)
|
|
GANETSKY_2017
|
NA
|
3.61% (2.30–5.37%)
|
|
HILL_2018
|
NA
|
3.29% (1.33–6.65%)
|
|
HUANG_2019
|
NA
|
2.52% (0.52–7.19%)
|
|
MANN_2018
|
NA
|
0.00% (0.00–3.18%)
|
|
NISHIJIMA_2012
|
0.00% (0.00–1.53%)
|
1.23% (0.26–3.57%)
|
|
PECK_2011
|
NA
|
0.00% (0.00–3.52%)
|
|
SCANTLING_2017
|
1.21% (0.15–4.31%)
|
1.2% (0.15–4.28%)
|
|
STANITSAS_2016
|
NA
|
0.00% (0.00–8.81%)
|
|
SWAP_2016
|
NA
|
2.31% (0.85–4.95%)
|
|
TAUBER_2009
|
4.00% (1.10–9.93%)
|
4.00% (1.10–9.93%)
|
|
TAYLOR_2012
|
NA
|
0.00% (0.00–4.25%)
|
|
No. studies
|
5
|
16
|
|
DB mean estimated risk
|
1.04% (0.15–2.49%)
|
1.70% (0.93–2.67%)
|
|
p value for heterogeneity
|
p = 0.0334
|
p = 0.0012
|
|
I2 statistic
|
62%
|
60%
|
- The results are presented as the mean estimates of delayed bleeding risk and 95% confidence intervals (in parentheses). GCS = Glasgow Coma Scale; MTBI = mild traumatic brain injury: includes only studies enrolling patients with TBI and a GCS ≥ 13; Sensitivity = includes all the studies considering unexplained deaths and patients lost at follow-up as events (i.e. delayed bleeding); No. studies = number of the studies included in the analysis; NA = not assessed in the corresponding original study
