Diagnoses | Final diagnosis positive / 4 h positive | Sensitivity% (95% CI) | Specificity% (95% CI) | PPV % (95% CI) | NPV % (95% CI) | |||||
---|---|---|---|---|---|---|---|---|---|---|
Interv. | Control | Interv. | Control | Interv. | Control | Interv. | Control | Interv. | Control | |
COPD with exacerbation | 27/29 | 28/24 | 89 (71–98) | 75 (55–89) | 94 (86–98) | 96 (89–99) | 83 (64–94) | 88 (68–97) | 96 (89–99) | 91 (83–97) |
Asthma with exacerbation | 2/2 | 3/3 | 0 (0–84) | 67 (9–99) | 98 (93–100) | 99 (94–100) | 0 (0–84) | 67 (9–99) | 98 (93–100) | 99 (94–100) |
Interstitial lung disease | 3/1 | 5/2 | 33 (1–91) | 0 (0–52) | 100 (97–100) | 98 (93–100) | 100 (3–100) | 0 (0–84) | 98 (93–100) | 95 (88–98) |
Pneumonia | 26/34 | 34/40 | 89 (70–98) | 88 (73–97) | 86 (77–93) | 86 (76–93) | 68 (50–83) | 75 (59–87) | 96 (88–99) | 94 (85–98) |
Pulmonary edema | 17/10 | 6/4 | 53 (28–77) | 33 (4–78) | 99 (94–100) | 98 (93–100) | 90 (56–100) | 50 (7–93) | 92 (84–96) | 96 (90–99) |
Para-pneumonic effusion | 14/14 | 14/7 | 71 (42–92) | 36 (13–65) | 96 (89–99) | 98 (92–100) | 71 (42–92) | 71 (29–96) | 96 (89–99) | 91 (83–96) |
Pleural empyemaa | 1/0 | 0/0 | – | – | – | – | – | – | – | – |
Pulmonary embolism | 3/11 | 2/7 | 100 (29–100) | 100 (16–100) | 92 (85–97) | 96 (89–98) | 27 (6–61) | 29 (4–71) | 100 (96–100) | 100 (96–100) |
Pneumothoraxa | 0/0 | 1/3 | – | 100 (3–100) | – | 98 (93–100) | – | 33 (1–91) | – | 100 (96–100) |
Systolic heart failure | 17/16 | 22/18 | 77 (50–93) | 59 (36–79) | 97 (91–99) | 94 (87–98) | 81 (54–96) | 72 (47–90) | 95 (89–99) | 90 (81–95) |
Non-systolic heart failure | 5/6 | 1/2 | 60 (15–95) | 100 (3–100) | 97 (92–99) | 99 (95–100) | 50 (12–88) | 50 (1–99) | 98 (93–100) | 100 (97–100) |
Acute myocardial infarction | 1/2 | 2/9 | 0 (0–98) | 50 (1–99) | 98 (93–100) | 92 (85–97) | 0 (0–84) | 11 (0–48) | 99 (95–100) | 99 (94–100) |
Anemia | 5/1 | 6/1 | 20 (1–72) | 0 (0–46) | 100 (96–100) | 99 (95–100) | 100 (3–100) | 0 (0–98) | 96 (91–99) | 94 (88–98) |
Malignancy | 8/2 | 19/7 | 25 (3–65) | 26 (9–51) | 94 (96–100) | 98 (92–100) | 100 (16–100) | 71 (29–96) | 94 (88–98) | 86 (77–92) |
Other diagnoses | 33/29 | 35/31 | 58 (39–75) | 60 (42–76) | 86 (76–93) | 86 (75–93) | 66(46–82) | 68 (49–83) | 83(71–90) | 81 (70–89) |