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Table 4 Univariate and multivariate analyses of factors affecting survival to discharge

From: Association between the body mass index and outcomes of patients resuscitated from out-of-hospital cardiac arrest: a prospective multicentre registry study

Variables

Univariate analysis

Multivariate analysis (N = 559)

Unadjusted OR

95% CI for the OR

p-value*

Adjusted OR

95% CI for the OR

p-value*

Age, (per year)

0.958

0.947–0.97

<.001

0.971

0.953–0.989

0.001

Sex, (Female/male)

0.61

0.43–0.867

0.006

0.789

0.478–1.302

0.354

Witnessed arrest (Yes/No)

1.695

1.171–2.453

0.005

1.434

0.849–2.422

0.178

Arrest location (Home/Others)

0.513

0.371–0.71

<.001

0.783

0.491–1.249

0.305

Bystander response (CPR performed/CPR not performed)

1.707

1.236–2.356

0.001

1.194

0.741–1.923

0.467

First monitored rhythm (Shockable/Non-shockable)

6.098

4.244–8.761

<.001

2.762

1.505–5.068

0.001

Hypertension (Present/Absent)

0.64

0.464–0.883

0.007

1.073

0.64–1.799

0.790

Diabetes (Present/Absent)

0.409

0.286–0.583

<.001

0.381

0.221–0.657

0.001

Dyslipidaemia (Present/Absent)

1.101

0.579–2.093

0.769

   

No flow time, (per minute)

0.984

0.964–1.005

0.142

   

Low flow time, (per minute)

0.939

0.927–0.95

<.001

0.969

0.953–0.986

<.001

Pre-hospital ROSC (Observed/Not observed)

10.845

7.075–16.624

<.001

2.161

1.011–4.619

0.047

Pre-hospital adrenaline (Used/Not used)

0.474

0.273–0.824

0.008

0.639

0.283–1.443

0.281

Pre-hospital airway

 Bag-valve mask

Reference

   

 Supraglottic airway

0.802

0.569–1.129

0.206

   

 Endotracheal intubation

0.703

0.413–1.199

0.196

   

Mental state at admission

 Alert

Reference

Reference

 Drowsy to stuporous

0.43

0.14–1.321

0.141

1.685

0.433–6.559

0.067

 Coma

0.062

0.025–0.158

<.001

0.451

0.146–1.397

0.005

Reperfusion attempted

 None

Reference

Reference

 CAG only

5.003

3.307–7.567

<.001

1.58

0.84–2.973

0.197

 CAG and PCI

2.832

1.764–4.548

<.001

0.923

0.438–1.945

0.385

 tPA

1.262

0.652–2.443

0.490

1.293

0.555–3.013

0.765

 TTM (Performed/Not performed)

1.34

0.962–1.865

0.083

   

 pH

89.557

34.575–231.976

<.001

1.572

0.375–6.59

0.536

 Lactate (per mmol/l)

0.868

0.835–0.903

<.001

0.958

0.907–1.011

0.115

 Glucose (per mg/dl)

0.998

0.997–0.999

0.002

1

0.998–1.002

0.985

 First systolic BP after ROSC, (per mmHg)

1.008

1.004–1.012

<.001

1.009

1–1.018

0.054

 First diastolic BP after ROSC, (per mmHg)

1.021

1.014–1.028

<.001

0.999

0.983–1.015

0.931

 First pulse rate after ROSC, (per beat/min)

1.003

0.997–1.008

0.340

   

BMI, kg/m2

 18.5 to 24.9

Reference

Reference

  < 18.5

0.531

0.318–0.889

0.030

0.854

0.425–1.719

0.889

 25.0 to 29.9

0.881

0.606–1.282

0.697

0.856

0.49–1.495

0.861

  > 30.0

1.004

0.495–2.035

0.474

0.621

0.211–1.823

0.496

  1. Abbreviations: BMI body mass index, CAG coronary angiography, CI confidence interval, CPR cardiopulmonary resuscitation, OR odds ratio, PCI percutaneous coronary intervention, ROSC return of spontaneous circulation, tPA tissue plasminogen activator, TTM targeted temperature management
  2. *p < 0.05 was significant