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Table 4 Univariate and multivariate analyses of factors affecting survival to discharge

From: Association between the body mass index and outcomes of patients resuscitated from out-of-hospital cardiac arrest: a prospective multicentre registry study

Variables Univariate analysis Multivariate analysis (N = 559)
Unadjusted OR 95% CI for the OR p-value* Adjusted OR 95% CI for the OR p-value*
Age, (per year) 0.958 0.947–0.97 <.001 0.971 0.953–0.989 0.001
Sex, (Female/male) 0.61 0.43–0.867 0.006 0.789 0.478–1.302 0.354
Witnessed arrest (Yes/No) 1.695 1.171–2.453 0.005 1.434 0.849–2.422 0.178
Arrest location (Home/Others) 0.513 0.371–0.71 <.001 0.783 0.491–1.249 0.305
Bystander response (CPR performed/CPR not performed) 1.707 1.236–2.356 0.001 1.194 0.741–1.923 0.467
First monitored rhythm (Shockable/Non-shockable) 6.098 4.244–8.761 <.001 2.762 1.505–5.068 0.001
Hypertension (Present/Absent) 0.64 0.464–0.883 0.007 1.073 0.64–1.799 0.790
Diabetes (Present/Absent) 0.409 0.286–0.583 <.001 0.381 0.221–0.657 0.001
Dyslipidaemia (Present/Absent) 1.101 0.579–2.093 0.769    
No flow time, (per minute) 0.984 0.964–1.005 0.142    
Low flow time, (per minute) 0.939 0.927–0.95 <.001 0.969 0.953–0.986 <.001
Pre-hospital ROSC (Observed/Not observed) 10.845 7.075–16.624 <.001 2.161 1.011–4.619 0.047
Pre-hospital adrenaline (Used/Not used) 0.474 0.273–0.824 0.008 0.639 0.283–1.443 0.281
Pre-hospital airway
 Bag-valve mask Reference    
 Supraglottic airway 0.802 0.569–1.129 0.206    
 Endotracheal intubation 0.703 0.413–1.199 0.196    
Mental state at admission
 Alert Reference Reference
 Drowsy to stuporous 0.43 0.14–1.321 0.141 1.685 0.433–6.559 0.067
 Coma 0.062 0.025–0.158 <.001 0.451 0.146–1.397 0.005
Reperfusion attempted
 None Reference Reference
 CAG only 5.003 3.307–7.567 <.001 1.58 0.84–2.973 0.197
 CAG and PCI 2.832 1.764–4.548 <.001 0.923 0.438–1.945 0.385
 tPA 1.262 0.652–2.443 0.490 1.293 0.555–3.013 0.765
 TTM (Performed/Not performed) 1.34 0.962–1.865 0.083    
 pH 89.557 34.575–231.976 <.001 1.572 0.375–6.59 0.536
 Lactate (per mmol/l) 0.868 0.835–0.903 <.001 0.958 0.907–1.011 0.115
 Glucose (per mg/dl) 0.998 0.997–0.999 0.002 1 0.998–1.002 0.985
 First systolic BP after ROSC, (per mmHg) 1.008 1.004–1.012 <.001 1.009 1–1.018 0.054
 First diastolic BP after ROSC, (per mmHg) 1.021 1.014–1.028 <.001 0.999 0.983–1.015 0.931
 First pulse rate after ROSC, (per beat/min) 1.003 0.997–1.008 0.340    
BMI, kg/m2
 18.5 to 24.9 Reference Reference
  < 18.5 0.531 0.318–0.889 0.030 0.854 0.425–1.719 0.889
 25.0 to 29.9 0.881 0.606–1.282 0.697 0.856 0.49–1.495 0.861
  > 30.0 1.004 0.495–2.035 0.474 0.621 0.211–1.823 0.496
  1. Abbreviations: BMI body mass index, CAG coronary angiography, CI confidence interval, CPR cardiopulmonary resuscitation, OR odds ratio, PCI percutaneous coronary intervention, ROSC return of spontaneous circulation, tPA tissue plasminogen activator, TTM targeted temperature management
  2. *p < 0.05 was significant