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Table 3 Univariate and multivariate analyses of factors affecting favourable neurologic outcomes

From: Association between the body mass index and outcomes of patients resuscitated from out-of-hospital cardiac arrest: a prospective multicentre registry study

Variables Univariate analysis Multivariate analysis (N = 559)
Unadjusted OR 95% CI for the OR p-value* Adjusted OR 95% CI for the OR p-value*
Age, (per year) 0.946 0.933–0.959 <.001 0.927 0.901–0.953 <.001
Sex, (Female/male) 0.573 0.388–0.844 0.005 1.307 0.617–2.766 0.484
Witnessed arrest (Yes/No) 1.503 1.004–2.249 0.045 0.961 0.461–2.003 0.916
Arrest location (Home/Others) 0.476 0.337–0.672 <.001 0.703 0.366–1.35 0.290
Bystander response (CPR performed/CPR not performed) 2.069 1.463–2.927 <.001 0.658 0.325–1.332 0.245
First monitored rhythm (Shockable/Non-shockable) 14.456 9.456–22.101 <.001 5.869 2.646–13.018 <.001
Hypertension (Present/Absent) 0.573 0.406–0.808 0.002 1.193 0.579–2.459 0.632
Diabetes (Present/Absent) 0.449 0.302–0.667 <.001 0.547 0.252–1.188 0.127
Dyslipidaemia (Present/Absent) 1.685 0.882–3.22 0.114    
No flow time, (per minute) 0.992 0.97–1.014 0.470    
Low flow time, (per minute) 0.907 0.891–0.923 <.001 0.962 0.938–0.987 0.003
Pre-hospital ROSC (Observed/Not observed) 19.647 12.791–30.18 <.001 3.762 1.442–9.813 0.007
Pre-hospital adrenaline (Used/Not used) 0.446 0.232–0.858 0.016 1.103 0.319–3.814 0.877
Pre-hospital airway
 Bag-valve mask Reference    
 Supraglottic airway 0.769 0.537–1.101 0.152    
 Endotracheal intubation 0.606 0.337–1.092 0.095    
Mental state at admission
 Alert Reference Reference
 Drowsy to stuporous 0.357 0.136–0.938 0.037 3.924 0.81–19.022 0.006
 Coma 0.036 0.016–0.081 <.001 0.226 0.065–0.782 <.001
Reperfusion attempted
 None Reference Reference
 CAG only 9.106 5.818–14.252 <.001 2.636 1.193–5.823 0.057
 CAG and PCI 7.482 4.457–12.561 <.001 5.027 1.869–13.521 0.001
 tPA 0.821 0.305–2.207 0.696 0.353 0.069–1.802 0.021
 TTM (Performed/Not performed) 0.934 0.658–1.327 0.705    
 pH 632.387 193.43–999.999 <.001 1.706 0.196–14.837 0.628
 Lactate (per mmol/l) 0.858 0.821–0.897 <.001 0.972 0.893–1.058 0.513
 Glucose (per mg/dl) 0.998 0.996–0.999 0.008 0.998 0.994–1.001 0.136
 First systolic BP after ROSC, (per mmHg) 1.007 1.003–1.011 0.003 1.011 0.996–1.025 0.145
 First diastolic BP after ROSC, (per mmHg) 1.024 1.017–1.032 <.001 1.013 0.991–1.036 0.253
 First pulse rate after ROSC, (per beat/min) 1.000 0.994–1.005 0.993    
BMI, kg/m2
 18.5 to 24.9 Reference Reference
  < 18.5 0.305 0.155–0.601 0.003 0.656 0.185–2.325 0.358
 25.0 to 29.9 0.929 0.627–1.376 0.366 0.658 0.301–1.441 0.187
  > 30.0 1.401 0.687–2.859 0.040 2.722 0.65–11.401 0.087
  1. Abbreviations: BMI body mass index, CAG coronary angiography, CI confidence interval, CPR cardiopulmonary resuscitation, OR odds ratio, PCI percutaneous coronary intervention, ROSC return of spontaneous circulation, tPA tissue plasminogen activator, TTM targeted temperature management
  2. *p < 0.05 was significant