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Table 1 Observational studies using ECMO in adult septic shock, modified and extended according to Riera [13] et al.

From: Septic shock: ECMO beyond ARDS? Introducing the Simon two-stage protocol when randomisation is considered unethical

StudyNSites of infection
%
ECMO
configuration
Hospital
Survival
%
Brechot et al. [14]14Pneumonia bacterial 79
Abdomen 14,3
Peripheral va 36%
Switch to vv
71
Huang et al. [15]52Pneumonia 48
Abdomen 23
Urinary tract 9,6
Peripheral va15
Cheng et al. [16]108Pneumonia bacterial 40
Myocarditis 25
Primary bloodstream 19,4
Peripheral va 78,7
Peripheral vv 21,3
28,7
Park et al. [17]32Pneumonia bacterial 34,4
Abdomen 21,9
Urinary tract 12,5
Peripheral va21,9
Cheng et al. [18]151Pneumonia 50,3
Myocarditis 19,9
Bloodstream 14,6
Abdomen 7,6
Peripheral va 66,9
vv 33,1
29,8
Von Bahr et al. [19]255Pneumonia bacterial 53
Pneumonia viral 12,5
vv 68
switch to va
peripheral 21
switch to vv 16
64
Takauji et al. [20]40Pneumonia 62,5
Abdomen 20
Urinary tract 7,5
vv47,5
Yeo et al. [21]8Pneumonia n = 5
Extra-pulmonary n = 3
vva50
Choi et al. [22]28Pulmonary 46,4
Abdomen 14,3
Genitourinary 7,1
Skin or soft tissue 14,3
Cardiovascular 7,1
Central nerve system 3,6
Catheter-induced 3,6
Other 3,6
vv, va, vva35,7
Ro et al. [23]71Pneumonia 70
Abdomen 11
Urinary tract 5
Other 14
va7
Vogel et al. [24]12Septic cardiomyopathy n = 12vva75
Banjas et al. [25]19Pneumonia 53
Abdomen 42
Soft tissue 5
vv, va, vva42
Falk et al. [26]37Lung n = 21
Gut n = 2
Pyelonephritis n = 4
Fasciitis n = 4
Urine n = 1
Blood n = 4
Myocarditis n = 1
vv, vaDistributive
shock 70,6
Cytotoxic
Cardiac failure
90,0