| |
Patients treated N (%) N = 104,862
|
Deaths avoided N (95% CI)
|
Deaths avoided per 10,000 patients N (95% CI)
|
Number needed to treat to avoid one death
|
|---|
|
Based on predicted probabilities
|
|
Current strategya
|
9915 (11)
|
55 (54–57)
|
5 (5–5)
|
180
|
|
All prehospital
|
79,430 (76)
|
224 (220–228)
|
21 (21–22)
|
355
|
|
All in hospital
|
63,246 (60)
|
146 (144–149)
|
14 (14–14)
|
430
|
|
Based on observed probabilities (sensitivity analysis)b
|
|
Current strategya
|
9915 (11)
|
168 (157–178)
|
16 (15–17)
|
59
|
|
All prehospital
|
79,430 (76)
|
323 (305–341)
|
31 (29–33)
|
244
|
|
All in hospital
|
63,246 (60)
|
240 (226–253)
|
22 (21–24)
|
273
|
- NNT Number Needed to Treat
- aCurrent strategy observed in the UK-TARN data based on clinical judgment and current guidelines in UK
- bSensitivity analysis based on observed deaths due to bleeding
